Results 31 to 40 of about 23,097 (201)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Looking around: comparing eye-tracking metrics among designers with and without ADHD during convergent and divergent thinking tasks

Design Science
Divergent and convergent thinking are critical processes in design, ensuring that solutions are plentiful, widely applicable, original and useful.
Rachel Kimball, Rohan Prabhu
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Role of Non-Representational Hand Gestures in Creative Thinking

Languages
Previous studies suggest that representational gestures support divergent thinking and that mental imagery is necessary for gestures to aid convergent thinking. However, less is known about non-representational gesture use (i.e., beat and palm-revealing)
Gyulten Hyusein, Tilbe Göksun
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Creative Thinking Process and Brain Dominance: Divergent and Convergent Thinking in Originality and Elaboration

Journal of Mathematics Instruction, Social Research and Opinion
The creative thinking process results from the interaction between divergent and convergent thinking, which complement each other and are influenced by brain hemisphere dominance in processing information.
Bayu Sukmaangara, Muhamad Gani Rohman
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Effectiveness of Paul’s critical thinking model on students’ critical thinking disposition and life skills with regard to the moderating role of divergent and convergent thinking styles [PDF]

فصلنامه نوآوری‌های آموزشی, 2014
The aim of this study was the investigation of effectiveness of Paul’s critical thinking model on critical thinking disposition and life skills with regard to the mediating role of divergent and convergent thinking styles.
Touraj Hāshemi, Mansour Bayrāmi, Rahim Badri, Mirmahmoud Mirnasab, Mortezā Razaviyān Shād   +4 more
doaj  

Convergent creative thinking performance is associated with white matter structures: Evidence from a large sample study

NeuroImage, 2020
In laboratory settings, creativity is measured using tasks of divergent as well as convergent thinking. It has been suggested that brain connectivity is important for creativity.
Hikaru Takeuchi, Yasuyuki Taki, Izumi Matsudaira, Shigeyuki Ikeda, Kelssy H. dos S. Kawata, Rui Nouchi, Kohei Sakaki, Seishu Nakagawa, Takayuki Nozawa, Susumu Yokota, Tsuyoshi Araki, Sugiko Hanawa, Ryo Ishibashi, Shohei Yamazaki, Ryuta Kawashima   +14 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source