Results 51 to 60 of about 21,123 (242)

CREATIVITY AND CONVERGENT THINKING: REFLECTIONS, CONNECTIONS AND PRACTICAL CONSIDERATIONS

RUDN Journal of Psychology and Pedagogics, 2016
Creativity is conceived as the ability to generate new, original ideas that are meaningful and valuable in their context. Models have often debated the role of divergent and convergent thinking within creativity. This paper focuses on convergent thinking
Todd Lubart
doaj  

Multi-Trait Multi-Method Matrices for the Validation of Creativity and Critical Thinking Assessments for Secondary School Students in England and Greece

International Journal of Assessment Tools in Education, 2018
The aim of this paper is the validation ofmeasurement tools which assess critical thinking and creativity as generalconstructs instead of subject-specific skills.
Ourania Maria Ventista
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Joint Action Enhances Cohesion and Positive Affect, but Suppresses Aspects of Creativity When Combined With Shared Goals

Frontiers in Psychology, 2019
We aimed to examine the link between two types of joint action (synchrony and asynchrony) and creativity (both divergent thinking and convergent thinking) using an established experimental paradigm.
Reneeta Mogan, Joseph Bulbulia, Ronald Fischer   +2 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Pengaruh Model Pembelajaran dan Gaya Berpikir Terhadap Hasil Belajar Mata Kuliah Filsafat Pendidikan

Jurnal Teknologi Pendidikan, 2018
This study aims at revealling the effect of instructional models and students thinking styles on the students learning outcomes of the educational philosophy course at the IAIN Palu.
Hamlan Andi Baso Malla, Herlina Herlina, Misnah Misnah   +2 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Evaluating the impact of a short bout of stair-climbing on creative thinking in a between-subjects pretest posttest comparison study

Scientific Reports
Recent studies have indicated potential links between short bouts of physical activity like stair-climbing and enhanced creative thinking. However, previous research featured limitations, such as using an uncommon 3 flights round-trip design and lacking ...
Chihiro Kawashima, Chong Chen, Kosuke Hagiwara, Tomohiro Mizumoto, Mino Watarai, Takaya Koga, Fumihiro Higuchi, Yuko Fujii, Emi Okabe, Shin Nakagawa   +9 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source