Results 71 to 80 of about 572,188 (337)
Al-Mustansiriyah Journal of Science, 2020 Polycyclic aromatic hydrocarbons (PAHs) are recognized as a toxic, mutagenic and/or carcinogenic compounds, and their pollution of soil and aquifer is of increasing environmentally risk. Laccases (E.C.
Ali A. Taha +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Corela, 2019 Nowadays, our technological environment is characterized by a total computer dissemination in the intelligent and connected objects. In this context of Ambient Intelligence (Zelkha et al., 1998) the domotic devices are deployed in so-called '' natural ...
François Perea
doaj +1 more source
Neural synchrony in mother–child conversation: Exploring the role of conversation patterns
Social Cognitive and Affective Neuroscience, 2020 Conversations are an essential form of communication in daily family life. Specific patterns of caregiver–child conversations have been linked to children’s socio-cognitive development and child-relationship quality beyond the immediate family ...
Trinh Nguyen +5 more
semanticscholar +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
AN APPROACH TO ENGLISH CONVERSATION WITH IRAQI UNIVERSITY STUDENTS [PDF]
آداب الرافدين, 1974 We maintain that the most difficult of the four skills involved in learning a foreign language are speaking and writing. The other two skills being listening and reading.
M. Al-Sawaf
doaj +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
BMC GenomicsBackground Banna caecilian (Ichthyophis bannanicus) was the first species of Gymnophiona to be discovered in China, with unique lifestyles and characteristics.
Jieling Lai +6 more
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source