Results 61 to 70 of about 1,258,142 (306)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Practices of everyday telephone conversation closings: when the call does not close
Calidoscópio, 2010 This paper studies everyday telephone conversation closings in the framework of ethnomethodological Conversation Analysis. Through the contributions of Schegloff and Sacks (1973) and Button (1987; 1990), among others, it aims to show some practices used ...
Roberto Perobelli de Oliveira +1 more
doaj +1 more source
THE FUNCTIONS OF PHATIC EXPRESSIONS IN TRADITIONAL SELLING AND BUYING [PDF]
, 2016 Selling and buying is a social praxis commonly found in daily activities. Traditional selling and buying is generally conducted in local language or dialect.
Hadiati , Chusni
core
Structural equation modeling of political discussion networks [PDF]
, 2017 This study conducts structural equation modeling (SEM) of political discussion networks. It examines multiple relationships between political discussion networks—network size and non-kin composition, political efficacy, and neighborhood conversation ...
Li, Xiaoqian
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Interactional integration of talk and note-taking
Psychology of Language and Communication, 2021 This paper contributes to the current line of research that examines how participants interactionally engage in simultaneous multiple courses of actions.
Nielsen Søren Beck
doaj +1 more source
The Role of Mediators in Science Museums: An Analysis of Conversations and Interactions of Brazilian Families in Free and Mediated Visits to an Interactive Exhibition on Biodiversity [PDF]
, 2022 Luisa Massarani +10 more
openalex +1 more source
PRAGMATIC IMPERATIVES IN THE DIALOGS OF SEMAR MBANGUN GEDHONG KENCANA STORY PERFORMED BY KI MUJAKA JAKA RAHARJA [PDF]
, 2010 The Javanese shadow puppet theater is still existed in the globalization era because it is not only seen from the visual or aesthetic aspects but also from the deep meaning beyond the performance so that wayang, for Javanese people, becomes tontonan ...
S. Hesti, Heriwati
core
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source