Results 71 to 80 of about 175,823 (293)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Conversation Analysis and the Study of Bilingual Interaction
Nordlyd: Tromsø University Working Papers on Language & Linguistics, 2004 This paper is written by a linguist who is working with language in interaction within the paradigm of Conversation Analysis. The topic of the paper was inspired by a seminar where the socalled Køge Project researchers, who investigate Turkish-Danish ...
Jakob Steensig
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Applying Conversation Analysis to Real-world Concerns
Working Papers in Applied Linguistics and TESOL, 2015 A few weeks ago, I sat in the audience of an atypical professional panel at an uplifting conference. The panel and audience members, all enthusiastic alumni and students of my alma mater’s English Department, were discussing the career paths they had (or
Catherine Box, Nancy Boblett
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
An initial investigation of the usability of fictional conversation for doing conversation analysis
, 1987 This paper proposes that fictional conversations be taken seriously as objects for conversation analysis. It also goes some small way towards exemplifying such an analysis.
McHoul, A.W.
core
Memory in interaction: an analysis of repeat calls to a home birth helpline [PDF]
, 2007 Drawing on a corpus of 80 calls to a Home Birth helpline, we use conversation analysis to analyze how callers and call takers display to one another that they are talking for a second or subsequent time.
Celia Kitzinger +3 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Conversation Analysis of Boke-tsukkomi Exchange in Japanese Comedy
, 2011 This article analyses and discusses what Japanese comical exchange called boke-tsukkomi is like and how it draws laughter. Conversation analysis and incongruity resolution are used as methods for the examination of the boke-tsukkomi examples.
Hideo Tsutsumi
core +1 more source