Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Applying Conversation Analysis to Real-world Concerns
Working Papers in Applied Linguistics and TESOL, 2015 A few weeks ago, I sat in the audience of an atypical professional panel at an uplifting conference. The panel and audience members, all enthusiastic alumni and students of my alma mater’s English Department, were discussing the career paths they had (or
Catherine Box, Nancy Boblett
doaj +1 more source
Teacher talk about student characteristics and patterns of behaviour : a thesis presented in partial fulfillment of the requirements for the degree of Master of Arts in Psychology at Massey University, Albany Campus, Auckland, New Zealand [PDF]
, 2007 This thesis reports on the discourse analysis of two groups of secondary school teachers' conversation about student behaviour. The study involved a two stage analysis. The teachers' conversation was first analysed according to its reflection of teachers'
Bester, Vasti
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
PRAGMATIC IMPERATIVES IN THE DIALOGS OF SEMAR MBANGUN GEDHONG KENCANA STORY PERFORMED BY KI MUJAKA JAKA RAHARJA [PDF]
, 2010 The Javanese shadow puppet theater is still existed in the globalization era because it is not only seen from the visual or aesthetic aspects but also from the deep meaning beyond the performance so that wayang, for Javanese people, becomes tontonan ...
S. Hesti, Heriwati
core
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Co-Constructing Writing Knowledge: Students’ Collaborative Talk Across Contexts [PDF]
, 2017 Although compositionists recognize that student talk plays an important role in learning to write, there is limited understanding of how students use conversational moves to collaboratively build knowledge about writing across contexts.
Campbell, Lillian +3 more
core +1 more source
Planning for teaching early mathematics: negotiation of shared intentions [PDF]
, 2019 This paper uses thematic analysis to investigate how shared intentions for the Maths4all project were negotiated. Individuals or pairs prepared seven mathematical activity guides forpreschool and primary school groups.
Farrell, Thérèse +3 more
core +1 more source
The Role of Mediators in Science Museums: An Analysis of Conversations and Interactions of Brazilian Families in Free and Mediated Visits to an Interactive Exhibition on Biodiversity [PDF]
, 2022 Luisa Massarani +10 more
openalex +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source