Results 61 to 70 of about 1,269,131 (329)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Analysis of Courtroom Conversation in Philadelphia Movie [PDF]
, 2013 Bahasa memiliki peran penting bagi kehidupan manusia. Bahasa tidak hanya digunakan sebagai media komunikasi namun juga sebagai sarana untuk menunjukan keberadaan seseorang dalam lingkungannya.
Agustina, A. K. (Agustina)
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Spoken Interaction: a sample of conversation analysis
RHS Revista Humanismo y Sociedad, 2017 In this paper an approach to the Conversation Analysis (CA) methodology is proposed. This methodology was used to collect and analyze a spontaneously and naturally spoken interaction.
Nelson D’olivares Durán +1 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The Communication between a Child Patient who was Exposed to Domestic Violence and the Medical Team
Dilbilim Araştırmaları Dergisi, 2003 The aim of this study is to reveal the dimensions of the interaction between the child patient and the health team responsible for delivery. The communication model between the patient and the medical team, namely the nurse and the other personnel, is ...
Seyyare Duman
doaj
Practices of everyday telephone conversation closings: when the call does not close
Calidoscópio, 2010 This paper studies everyday telephone conversation closings in the framework of ethnomethodological Conversation Analysis. Through the contributions of Schegloff and Sacks (1973) and Button (1987; 1990), among others, it aims to show some practices used ...
Roberto Perobelli de Oliveira +1 more
doaj +1 more source
THE FUNCTIONS OF PHATIC EXPRESSIONS IN TRADITIONAL SELLING AND BUYING [PDF]
, 2016 Selling and buying is a social praxis commonly found in daily activities. Traditional selling and buying is generally conducted in local language or dialect.
Hadiati , Chusni
core
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source