Results 41 to 50 of about 1,961 (282)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi +6 more
wiley +1 more source
Structural Discourse Markers in German Palliative Care Interactions
LanguagesThe aim of this study is to provide a systematic account of structural discourse markers operating at a conversational macro-level in German Palliative Care interactions, focusing on their frequency, distribution, co-occurrence, and speaker-group ...
Aaron Schmidt-Riese
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
“Bye alligator,” : mediated discourse as learnable social interaction: a study of the language of novice users of communication channels. [PDF]
, 2004 Polyvocality, according to Bakhtin (1986), is integral to all human communication: our understanding of any text is informed by our knowledge of its history of use.
Gillen, Julia, Goddard, Angela
core
Making sense of girls empowerment in Sierra Leone: a conversation [PDF]
, 2021 This Testify article features a conversation about the emancipatory potentials and pitfalls of girls empowerment as practiced, experienced, and judged by Sierra Leonean activists.
Menzel, Anne +5 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Med Student, Patient's Perspective
Voices in Bioethics, 2014 First year students at the University of Michigan Medical School are sent in pairs to patients’ homes to help them appreciate the patient’s perspective. As we walked out of Mrs. D’s apartment, my partner said, “Go home and write your essay.
Sarah Baruch
doaj +1 more source