Results 111 to 120 of about 545,698 (316)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Comportamento ingestivo e desempenho de ovinos em pastagem de azevém anual (Lolium multiflorum Lam.) com diferentes massas de forragem Ingestive behaviour and performance of sheep grazing Italian ryegrass (Lolium multiflorum Lam.) pasture with different herbage masses

open access: yesRevista Brasileira de Zootecnia, 2007
Objetivou-se avaliar o comportamento ingestivo e o desempenho de ovinos em pastagem de azevém anual (Lolium multiflorum Lam.) sob pastejo contínuo e com diferentes massas de forragem: baixa: 1.000 a 1.200 kg/ha MS; intermediária: 1.400 a 1.600 kg/ha MS ...
Juliano Roman   +5 more
doaj   +1 more source

solar conversion efficiency

open access: yes, 2014
Citation: 'solar conversion efficiency' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.S05728 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Technical efficiency and conversion to organic farming: the case of France

open access: yes
Using a panel of French crop farms, we test whether farmers’ technical efficiency under conventional practices is a significant driver of conversion to organic farming.
Laure Latruffe, Céline Nauges
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Ultra-broadband wavelength conversion based on four-wave mixing in a Raman DFB fiber laser

open access: yes
We report highly efficient four-wave mixing (FWM) within a 30cm-long centre pi phase-shifted Raman DFB fiber laser with a continuous frequency tuning range of ~19.9 THz with the FWM conversion efficiency up to ...
Shi, J.D., Ibsen, M., Alam, S.-U.
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Frequency conversion to augment power conversion efficiency in photovoltaic devices

open access: yes2024 24th International Conference on Transparent Optical Networks (ICTON)
To attain high power conversion efficiencies in photovoltaic devices majorly requires proper matching between the optoelectronic properties of the photoactive layer and the solar emission spectrum for maximum absorption of the solar photon flux. Up- and down-conversion using rare earth-doped layers represent the predominantly used approaches to tune ...
Sandile Kumalo   +3 more
openaire   +2 more sources

High efficiency smart voltage regulating module for green mobile computing [PDF]

open access: yes, 2014
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.In this thesis a design for a smart high efficiency voltage regulating module capable of supplying the core of modern microprocessors incorporating dynamic ...
Tapou, Monaf Sabri
core  

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