Results 71 to 80 of about 598,938 (299)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Isolated, multiple-output voltage dc-to-dc converter [PDF]

open access: yes, 1969
Isolated, multiple output voltage dc-to-dc converter provides power for television transmitter used in space vehicles. The isolation is accomplished by using a single-end switching transformer circuit.

core   +1 more source

Research on Control Strategy of Electric Mining Dumper Converter

open access: yes机车电传动, 2020
Electric mining dumper has been a key research object in mining industry. Owing to its special operating conditions, the control mode of mining dumper needs to be well studied and selected.
Tao ZHANG, Yaping HE, Xi HE
doaj  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

An Advanced Three-Level Active Neutral-Point-Clamped Converter With Improved Fault-Tolerant Capabilities [PDF]

open access: yes, 2017
A resilient fault-tolerant silicon carbide (SiC) three-level power converter topology is introduced based on the traditional active neutral-point-clamped converter.
He, Jiangbiao   +2 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Dc to ac converter operates efficiently at low input voltages [PDF]

open access: yes, 1965
Self-oscillating dc to ac converter with transistor switching to produce a square wave output is used for low and high voltage power sources.

core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Using transfer ratio to evaluate EMC design of adjustable speed drive systems [PDF]

open access: yes, 2006
This paper proposes a way to evaluate the conducted electromagnetic compatibility performance of variable speed drive systems. It is considered that the measured noise level is determined by two factors, the level of the noise source and the conversion ...
Ferreira, B.   +4 more
core   +1 more source

Low-Frequency Oscillation Suppression of the Vehicle–Grid System in High-Speed Railways Based on H∞ Control

open access: yesEnergies, 2018
Recently, a traction blockade in the depots of numerous electric multiple units (EMUs) of high-speed railways has occured and resulted in some accidents in train operation.
Zhaozhao Geng   +3 more
doaj   +1 more source

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