Results 91 to 100 of about 214,349 (248)
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
A series-parallel load-resonant converter for a controlled-current arc-welding power supply [PDF]
A power supply incorporating a series-parallel load-resonant converter, capable of very efficient operation over a wide range of output power is presented. The series-parallel load-resonant converter is shown to have three pairs of resonant frequencies.
Pollock, Helen Geraldine Phyllis
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Conversores Push-Pull PWM CC-CC trifásicos alimentados em corrente [PDF]
, 2010 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2010In this thesis, a three-phase current-fed Push-Pull DC-DC converter and its version with active clamping ...
Andersen, Romero Leandro
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Study of Urban Rail Train Renewable Braking Energy Feedback System
机车电传动, 2015 In order to verify the function and reliability of urban rail train renewable energy feedback system, mathematical model of energy feedback converter with double-loop control strategy and SVPWM modulation was built, and the simulation and test were ...
JI Hui, LI Kunpeng, YI Yunlan
doaj
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
SSL2109T/AT/SSL2129AT controller for SSL applications Revision history Rev Date Description
, 2012 This document describes how to design a buck converter in a low-ripple configuration, using the SSL2109T/AT or SSL2129AT IC, with an external MOSFET. Specifically, selecting the MOSFET and implementing it is described.
Buck Converter, Down Converter
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