Results 101 to 110 of about 214,349 (248)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Efficiency of super capacitor banks used in regenerative breaking in hybrid electric vehicles [PDF]
The aim of this project was to build a supercapacitor bank, dc to dc converter, and testing rig to perform efficiency testing for various configurations of the super capacitor bank against various hybrid electric vehicle regenerative braking profiles.
Napier, David
core
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Vibration Response Analysis of Metro Vehicle Converter Cabinet Based on Finite Element Method
The vibration response analysis of metro vehicle converter cabinet was carried out based on FEM software HyperMesh and Virtual.Lab. The vibration acceleration response of converter cabinet lugs was obtained by modal analysis and correction, transfer ...
XIA Liang +5 more
doaj
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Conversor CC-CC modular isolado para elevadas tensões de entrada e de saída [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2014.Este trabalho apresenta uma nova estrutura de conversor CC-CC (Corrente Contínua para Corrente ...
Piontkewicz, Rodrigo José
core
Peak-Current-Mode Controlled DC-DC Converter Stability Analysis for Buck and Boost Topologies
reservedThis work deals with studying, both from the theoretical and experimental point of view, the stability of two DC-DC converter topologies that implement peak-current-mode control performed by Infineon’s proprietary IC’s.
BRESSAN, MARCO
core
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Conversor CC-CC buck+boost multinível bidirecional [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-graduação em Engenharia Elétrica, Florianópolis, 2013Este trabalho apresenta uma nova topologia de conversor cc-cc Buck+Boost bidirecional multinível ...
Costa, Levy Ferreira
core

