Results 71 to 80 of about 766,223 (354)

Study on debugging of lightning impulse voltage waveform for large capacity ±800kV converter transformer in high altitude area

Frontiers in Energy Research, 2023
The Qinghai-Henan ±800kV UHV DC power transmission project is an UHV channel specially constructed for clean energy delivery, ±800kV converter transformers of the project are assembled and tested in Xining at an altitude of 2500 m, full-wave lightning ...
Ling Jiang, Ling Jiang, Shengfu Wang, Shengfu Wang, Jun Kang, Xiaoku Yang, Xiaoku Yang, Xiuyuan Yao, Yitao Zhang, Yitao Zhang, Zhenghong Bao, Zhenghong Bao, Yongsheng Zhang   +12 more
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

A Novel DVR Topology to Compensate Voltage Swell, Sag, and Single-Phase Outage

Iranian Journal of Electrical and Electronic Engineering, 2021
Aim of this paper is to attain the highest voltage sag and swell compensation using a direct converter-based DVR topology. The projected DVR topology consists of a direct converter with bidirectional switches, a multi winding transformer with three ...
S. A. Rahman, S. Birhan, E. D. Mitiku, G. T. Aduye, P. Somasundaram   +4 more
doaj  

Dual Channel Control with DC Fault Ride Through for MMC-based, Isolated DC/DC Converter [PDF]

, 2017
This study is sponsored by the Engineering and Physical Sciences Research Council (EPSRC) grant no EP/K006428/1, 2013.D. Jovcic and H. Zhang are with the School of Engineering, University of Aberdeen, AB24 3UE, U.K.
Jovcic, Dragan, Zhang, Huibin
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Analysis of AC link topologies in non-isolated DC/DC triple active bridge converter for current stress minimization [PDF]

, 2017
This paper presents analysis of the non-isolated DC/DC triple active bridge (TAB) converter under various purely inductor-based AC link topologies. The objective of the analysis is to find the topology that incorporates the least value of the AC link ...
Aboushady, Ahmed A., Ahmed, Khaled H., Hebala, Osama M.   +2 more
core   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Research on Fire Suppression Characteristics of Compressed Air Foams in Full-Scale 220 kV Converter Transformer

Fire
To study the fire behavior of UHVDC (ultra-high-voltage direct current) converter transformers and the effectiveness of CAFs (compressed air foams) in suppressing fires, a full-scale model of a 220 kV converter transformer fire was constructed. The model
Yike Guo, Tao Chen, Biao Zhou, Peng Zhang, Yuwei Wang, Xuyao Wang, Danping Hao   +6 more
doaj   +1 more source