Results 121 to 130 of about 253,873 (303)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Review of Converter Circuits with Power Factor Correction
TechnologiesThis article reviews converter circuits with power factor correction considering issues that arise in implementing such circuits. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) procedure are employed for the review.
Angel Quiroga +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Grid-forming Control for Power Converters Based on Hybrid Energy Storage Systems During Islanding Operation [PDF]
RadioengineeringEnergy storage systems are increasingly playing a pivotal role in power systems. The combination of distributed sources and energy storage systems with local loads forms an autonomous distribution grid (ADG) capable of flexibly operating in either ...
H. V. Nguyen +7 more
doaj
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
IEEE AccessThis paper addresses the critical issue of efficient power management and hydrogen consumption in DC microgrids powered by fuel cells. A novel energy management strategy involving a State Machine control (SMC) combined with a Fractional Order ...
Shashi Bhushan Mohanty, Satyajit Mohanty
doaj +1 more source
Analog-to-digital conversion techniques for precision photometry [PDF]
Three types of analog-to-digital converters are described: parallel, successive-approximation, and integrating. The functioning of comparators and sample-and-hold amplifiers is explained.
Opal, Chet B.
core +1 more source
A hybrid multilevel converter for medium and high voltage applications [PDF]
, 2010 This paper investigates the suitability of the hybrid multilevel converter for medium and high voltage application. The converter operation, modulation, and capacitor voltage balancing method are described in detail.
Adam, Grain Philip +4 more
core