Results 111 to 120 of about 118,684 (252)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Pilot Protection for Converter-interconnected Lines Based on Multi-stage Mutation of Fault Current
Zhongguo dianliThe introduction of power electronic converters has altered the fault characteristics of the traditional power grids. Traditional differential protection is inadequate to meet protection requirements when AC lines experience faults, leading to reduced ...
Zhaoyi SHA +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
High-speed linear digital-to-analog converters
, 2017 The demands for ever higher data rates, overall system cost reduction and improved power efficiency, and the advances of nm IC technologies, are pushing the DA converters to ever higher speeds, in terms of bandwidth and sampling rate.
van Roermund, A.H.M., Radulov, G.I.
core
Análise de estabilidade e síntese de controle para conversores boost com correção do fator de potência através de uma abordagem LMI [PDF]
, 2015 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Automação e Sistemas, Florianópolis, 2015.O estágio de entrada da grande maioria dos equipamentos eletrônicos modernos ...
Roschild, Jônatas Matthies
core
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Z-source converters and their classifications
Impedance-source networks have gained attention as promising power conversion stages owing to their flexible step-up/down conversion ratios and high reliability with shoot-through protection. However, there are still limitations that hinder their further
Siwakoti, YP +3 more
core +1 more source
IET Power ElectronicsRenewable energy stations are often equipped with virtual synchronous generators (VSG) for frequency and voltage support, but the transient instability of VSGs and the weak overcurrent capacity constrain the safe and stable operation of Renewable energy ...
Ruifeng Zhao +6 more
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source