Results 91 to 100 of about 253,873 (303)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Comparison of performance and emission characteristics between ceramic and metallic catalytic converter [PDF]
, 2018 Catalytic converters have been widely used on vehicles and have already been proved for many years to be the most effective technical solution to reduce exhaust emissions from gasoline engines where ceramic and metallic catalytic converters are the most ...
W Abdul Rahman, Wan Fakhrurrazi
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Optimal Dynamic Analysis of Electrical/Electronic Components in Wind Turbines
Energies, 2017 Electrical and electronic components are very important subcomponents in modern industrial wind turbines. Complex multimegawatt wind turbines are continuously being installed both onshore and offshore, continuously increasing the demand for sophisticated
Fausto Pedro García Márquez +4 more
doaj +1 more source
Immediate Analysis of Periodic Steady States in Switched DC-DC Converters via SPICE [PDF]
, 2012 The method of immediate analysis of periodic steady states in switched DC-DC converters operating in the continuous current mode is described. The initial conditions, which correspond to the periodic steady state, are found in the first step.
Biolek, Dalibor +2 more
core +1 more source
Analog to Digital Conversion in Physical Measurements [PDF]
, 1999 There exist measuring devices where an analog input is converted into a digital output. Such converters can have a nonlinear internal dynamics. We show how measurements with such converting devices can be understood using concepts from symbolic dynamics.
Feudel, U. +3 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
SensorsMajor depressive disorder requires scalable, low-burden screening tools. We examined whether three-channel resting-state EEG can support reliable discrimination between major depressive disorder and healthy controls using a lightweight model compatible ...
Oana-Isabela Știrbu +4 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Computational Analysis of EEG Responses to Anxiogenic Stimuli Using Machine Learning Algorithms
Applied SciencesAnxiety disorders are commonly assessed using instruments such as HAM-A and GAD-7. These tools rely on patient self-report and clinician interpretation, which may introduce variability.
Felix-Constantin Adochiei +5 more
doaj +1 more source