Results 81 to 90 of about 108,139 (315)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
SensorsMajor depressive disorder requires scalable, low-burden screening tools. We examined whether three-channel resting-state EEG can support reliable discrimination between major depressive disorder and healthy controls using a lightweight model compatible ...
Oana-Isabela Știrbu +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
IEEE AccessA fault detection method for power conversion circuits using thermal images and a convolutional autoencoder is presented. The autoencoder is trained on thermal images captured from a commercial power module at randomly varied load currents and augmented ...
Noboru Katayama, Rintaro Ishida
doaj +1 more source
Switch-mode power converters : design and analysis /
, 2006 This book introduces an innovative, highly analytical approach to symbolic, closed-form solutions for switched-mode power converter circuits. This is a highly relevant topic to power electronics students and professionals who are involved in the design ...
Wu, Keng C.
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Pilot Protection for Converter-interconnected Lines Based on Multi-stage Mutation of Fault Current
Zhongguo dianliThe introduction of power electronic converters has altered the fault characteristics of the traditional power grids. Traditional differential protection is inadequate to meet protection requirements when AC lines experience faults, leading to reduced ...
Zhaoyi SHA +4 more
doaj +1 more source
, 2016 © The Institution of Engineering and Technology 2016. Impedance-sourced networks provide an efficient means of power conversion between source and load in a wide range of electric power conversion applications (dc-dc, dc-ac, ac-dc, and ac-ac).
Siwakoti, YP, Blaabjerg, F, Loh, PC
core +1 more source