Results 101 to 110 of about 108,139 (315)

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Modelling of Power Converters Using Z-Transform

open access: yes, 2013
The paper introduces a novel method of analysis and modelling of power electronic converters. Z-transform, numerical series (sequences) are used for both steady and transient states investigation of converters.
Branislav Dobrucky   +3 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

A Comparative Study of Harmonic Distortion in Multicarrier Based PWM Switching Techniques for Cascaded H-Bridge Inverters

open access: yesAdvances in Electrical and Computer Engineering, 2016
Multicarrier based PWM switching patterns are commonly utilized to control Cascaded H-bridge (CHB) inverters. The main contribution of this paper is to comprehensively investigate the effect of various multicarrier based PWM techniques on harmonic ...
HAMEDANI, P., SHOULAIE, A.
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Review of Converter Circuits with Power Factor Correction

open access: yesTechnologies
This article reviews converter circuits with power factor correction considering issues that arise in implementing such circuits. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) procedure are employed for the review.
Angel Quiroga   +2 more
doaj   +1 more source

Effect of CO2 on material and energy in dephosphorization converters

open access: yes工程科学学报, 2016
Based on the characteristics of CO2 at high temperature, material and energy models for CO2 using in a dephosphoriza-tion converter were established to verify the feasibility of CO2 for oxidation reactions.
LI Zhi-zheng, ZHU Rong, ZHU Yi-qiang
doaj   +1 more source

High-speed linear digital-to-analog converters

open access: yes, 2017
The demands for ever higher data rates, overall system cost reduction and improved power efficiency, and the advances of nm IC technologies, are pushing the DA converters to ever higher speeds, in terms of bandwidth and sampling rate.
van Roermund, A.H.M., Radulov, G.I.
core  

Z-source converters and their classifications

open access: yes
Impedance-source networks have gained attention as promising power conversion stages owing to their flexible step-up/down conversion ratios and high reliability with shoot-through protection. However, there are still limitations that hinder their further
Siwakoti, YP   +3 more
core   +1 more source

Conexão série-série de módulos CC-CC isolados [PDF]

open access: yes, 2015
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2015Esta tese apresenta a associação de conversores CC-CC de duas portas conectados em série-série tanto na ...
Bottion, Antonio José Bento
core  

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