Results 81 to 90 of about 1,012,747 (224)

On the product formula and convolution associated with the index Whittaker transform

, 2019
We deduce a product formula for the Whittaker $W$ function whose kernel does not depend on the second parameter. Making use of this formula, we define the positivity-preserving convolution operator associated with the index Whittaker transform, which is ...
Guerra, Manuel, Sousa, Rúben, Yakubovich, Semyon   +2 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Method of multilayer object sectioning based on a light scattering model

Компьютерная оптика, 2023
We discuss a problem of reconstructing (sectioning) multilayer object images in observed images obtained by focusing the imaging system on each layer and containing spurious blurry images of neighboring layers.
S.D. Bazhitov, A.V. Larichev, A.V. Razgulin, T.E. Romanenko   +3 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

On Restoration of the Blur Parameter in the Optical Sectioning Problem

Современные информационные технологии и IT-образование, 2022
The article considers the problem of finding the blur parameter between two images for the optical sectioning problem, in which the blur model has a natural optical origin associated with the use of incoherent white light as a radiation source in the ...
Sergey Bazhitov
doaj   +1 more source

Deep Convolutional Tables: Deep Learning Without Convolutions

IEEE Transactions on Neural Networks and Learning Systems
We propose a novel formulation of deep networks that do not use dot-product neurons and rely on a hierarchy of voting tables instead, denoted as Convolutional Tables (CT), to enable accelerated CPU-based inference. Convolutional layers are the most time-consuming bottleneck in contemporary deep learning techniques, severely limiting their use in ...
Shay Dekel, Yosi Keller, Aharon Bar-Hillel   +2 more
openaire   +3 more sources

Spatiotemporal Multi-Graph Convolution Network for Ride-Hailing Demand Forecasting

AAAI Conference on Artificial Intelligence, 2019
Region-level demand forecasting is an essential task in ridehailing services. Accurate ride-hailing demand forecasting can guide vehicle dispatching, improve vehicle utilization, reduce the wait-time, and mitigate traffic congestion.
Xu Geng, Yaguang Li, Leye Wang, Lingyu Zhang, Qiang Yang, Jieping Ye, Yan Liu   +6 more
semanticscholar   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source