Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Antiepileptic Potential of Justicia insularis Leaf Extract in Swiss Mice
Epilepsy is a prevalent neurological condition characterized by repetitive seizures, necessitating the exploration of efficacious treatments. Justicia insularis, a plant with a historical use in treating convulsions and epilepsy, has garnered attention ...
Nancy Elkanah +3 more
doaj +1 more source
Effect reversible inhibition of hippocampal CA1 rehion by lidocaine on amygdala kindling rata in rats [PDF]
In this study the role of CA1 region of dorsal hippocamus an amygdala kindling rate was investigated by bilateral microinjection of lidocaine into hippocampus.28 rats were divided into four groups.in group I:animals were implanted only with a tripolar ...
S.M Mortazavi +5 more
doaj
Comparing the Effects of Propofol and Sodium Thiopental in the Induction of Anesthesia for Electro Convulsive Therapy (ECT) [PDF]
Background & Objectives: ECT is one of the most common methods in treatment of different types of psychological disorder. The effectiveness of this therapy has direct relation to the duration of convulsion.
اخوان اکبری, قدرت +3 more
core
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Trombosis venosa cerebral asociada a consumo de sildenafil
Se presentó un paciente masculino de 59 años de edad, con antecedentes de hipertensión arterial y consumo regular de sildenafil, que ingresó en el servicio de ictus por presentar convulsión aguda y cefalea.
José Luis Miranda Hernández +4 more
doaj
Anticonvulsant effects of Cuminium cyminum L. seeds extracts and essential oil in mice
The anticonvulsant effects of aqueous and ethanolic extracts as well as essential oil of Cuminum cyminum L. seeds were studied in mice. In pentylenetetrazole test, the essential oil and the extracts of seeds prolonged the onset time of tonic convulsion ...
H Hosseinzadeh +3 more
doaj
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Teaching basic relaxation procedures to psychiatric patients receiving electronconvulsive therapy : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]
There has been no research on psychiatric patients examining the ability to remember relaxation skills whilst receiving electroconvulsive therapy.
Simons, Bruce Francis
core
Two Cases of Rare Post-spinal Complications: Hypertension, tachycardia, hyperpyrexia, localized clonic convulsion [PDF]
Jung‐Hee Lee +2 more
openalex +1 more source

