Results 121 to 130 of about 82,230 (340)

Continuous Monitoring via Tethered Electroencephalography of Spontaneous Recurrent Seizures in Mice

Frontiers in Behavioral Neuroscience, 2017
We describe here a simple, cost-effective apparatus for continuous tethered electroencephalographic (EEG) monitoring of spontaneous recurrent seizures in mice.
Na-Ryum Bin, Na-Ryum Bin, Hongmei Song, Hongmei Song, Chiping Wu, Marcus Lau, Shuzo Sugita, Shuzo Sugita, James H. Eubanks, James H. Eubanks, James H. Eubanks, James H. Eubanks, Liang Zhang, Liang Zhang, Liang Zhang   +14 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Cyto-architectonic and histochemical studies of the caudate nucleus in cat's brain with special reference to convulsion part Ⅲ. Histochemical study of ketoenoIic granules in areas of the caudate nucleus of cat's brain with convulsion [PDF]

, 1958
Ten per cent metrazol solution was experimental1y iniected in cat's and the changes of the ketoenolic granules (KEG) due to convulsion were histochemically investigated by the carbol fuesin jod method.
Nishiwaki, Korenobu
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

The The Effect of Tramadol Addiction on Convulsion and Related Factors

, 2020
Background: Tramadol is a drug used to control severe pain. Various side effects of this drug have been reported, one of the most important is seizures. The exact cause of tramadol-induced seizures is not known.
Zolfaghari 3, Pouneh, Pourmand 5, Kamran, Salari Zare 4, Mohammad, Ghodrati 2, Nasrin, Sohrabi 6*, Mohammad Bagher, Najafi 1, Ali   +5 more
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

INFANTILE CONVULSIONS [PDF]

The Journal of Nervous and Mental Disease, 1890
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openaire   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

General Anesthesia Management of Super Refractory Status Epilepticus in Anti-N-Methyl-D-Aspartate-Receptor (NMDAR) Meningitis

International Journal of Integrated Health Sciences
Background: Super Refractory Status Epilepticus poses significant management challenges, requiring intensive therapeutic approaches including general anesthesia.
Putri Shabrina Amalia, Irvan Setiawan, Annemarie Chrysantia Melati   +2 more
doaj   +1 more source