Results 111 to 120 of about 82,230 (340)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Cavernomatose cérébrale sporadique révélée par une crise convulsive: à propos d'un cas

The Pan African Medical Journal, 2018
La cavernomatose cérébrale est une pathologie rare pouvant être sporadique ou familiale autosomique dominante. Elle est caractérisée par la présence de cavernomes multiples du système nerveux central. Souvent asymptomatique, la pathologie peut se révéler
Doumbia Amadou, Koné Youssouf, Maïga Oumou, Koné Abdoulaye, Diarra Bréhima, Dembélé Adama, Diallo Mamahadou   +6 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Effect reversible inhibition of hippocampal CA1 rehion by lidocaine on amygdala kindling rata in rats [PDF]

Journal of Kerman University of Medical Sciences, 2002
In this study the role of CA1 region of dorsal hippocamus an amygdala kindling rate was investigated by bilateral microinjection of lidocaine into hippocampus.28 rats were divided into four groups.in group I:animals were implanted only with a tripolar ...
S.M Mortazavi, S.J Mirnajafezadeh, Y Fatolahi, M Alasavand, M.R Palvizan, M Rostampour   +5 more
doaj  

Human enteroviruses are not the cause of neurological impairments in children at the Korle-Bu Teaching Hospital

The Pan African Medical Journal, 2014
INTRODUCTION: Convulsions associated with fever and acute onset of unknown aetiology with case fatalities have become a long observed medical condition at the Child Health Department of the Korle-Bu Teaching Hospital.
Prudence Tettey, Ebenezer Badoe, Theophilus Adiku, Eva Obodai, John Kofi Odoom   +4 more
doaj   +1 more source

Children with Psychogenic Nonepileptic Seizures

Pediatric Neurology Briefs, 2019
Researchers from the Pediatric Health Information System hospital network analyzed a large multicenter retrospective cohort to determine differences in demographics, clinical characteristics, testing, treatment and healthcare use between children ages 8 ...
Aisha Gillan, Safiullah Shareef
doaj   +1 more source

CONVULSION AND ITS RELATION TO ANTI-DNA ANTIBODY LEVELS IN SYSTEMIC LUPUS ERYTHEMATOSUS [PDF]

, 1999
The neuropsychiatric manifestations of systemic lupus erythematosus are frequent. One of the most serious presentations is convulsion. This study was carried out to evaluate the relation between convulsion and anti-DNA antibody levels.
F. Shahram, A. Nadji, M. Akbarian, F. Gharibdoost, A. Djamshidi, F. Davatchi   +5 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Antiepileptic Potential of Justicia insularis Leaf Extract in Swiss Mice

Biology, Medicine & Natural Product Chemistry
Epilepsy is a prevalent neurological condition characterized by repetitive seizures, necessitating the exploration of efficacious treatments. Justicia insularis, a plant with a historical use in treating convulsions and epilepsy, has garnered attention ...
Nancy Elkanah, Michael Chuks Nnumolu, Jude Effiom Okokon, Uduak Peter Ise   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source