Results 101 to 110 of about 31,866 (253)
ILAE CLASSIFICATION OF THE EPILEPSIES: THE 2017 REVISION AND UPDATE
Эпилепсия и пароксизмальные состояния, 2017 The International League Against Epilepsy (ILAE) has developed and approved the Operational classification of seizure types 2017 and the Classification of the Epilepsies 2017 .
G. N. Avakyan +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Studies on the Interception of the Pathways of Epileptic Convulsion Part III. Histological Studies on the Some Areas of Cat Diencephalon Concerning to intercept Epileptic Convulsion [PDF]
, 1959 The precise histological examination revealed that the area, of which selectiv damaging intercepted the epileptic convulsion, corresponded to the bilateral small spherical regions having a diameter of 2-3mm with H(2) of Forel's field as its center.
Kanbayashi, Tsuneo
core
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
International Journal of Integrated Health SciencesBackground: Super Refractory Status Epilepticus poses significant management challenges, requiring intensive therapeutic approaches including general anesthesia.
Putri Shabrina Amalia +2 more
doaj +1 more source
پزشکی بالینی ابن سینا, 1999 Pre-eclampsia is one of the common complications in pregnancy and it is one of three causes of maternal mortality. The major cause of death in pre-eclampsia is adding convulsion and change to eclampsia.
Soghra Rabiei, Nadereh Behtash
doaj
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source