Results 81 to 90 of about 82,230 (340)

Studies on the Interception of the Pathways of Epileptic Convulsion Part I. Demaging the Pathways of Epileptic Convulsion with the Horsley-Clarke's Stereotaxic Apparatus [PDF]

, 1959
In order to clarifing the pathways of epileptic convulsion, the following experiments were performed by the author. The same fieldes in the diencephalon of the cat were selectively damaged with the Horsley-Clarke's stereotaxic apparatus, and I-3 weeks ...
Kanbayashi, Tsuneo
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Relationship between Iron Deficiency Anemia and Febrile Convulsion in 6-Month to 5-Year-Old Children in Hazrat Fatemeh Masomeh Educational and Treatment Center, Qom University of Medical Sciences, Iran

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2015
Background and Objectives: Febrile convulsion (FC) is the most common seizure disorder in children and is seen in 2-5% of children under 5 years of age. This study was performed to determine the relationship between febrile convulsion and iron deficiency
Mohsen Molla Mohammadi, Javad Tafaroji
doaj  

The effect of epilepsy on pregnancy outcomes

Van Tıp Dergisi, 2018
INTRODUCTION: Approximately 25% of epilepsy cases are in reproductive ages, their seizures are kept under control by the current anti-epileptic drugs, and pregnancy rates are higher in these cases.
Numan Çim, Harun Egemen Tolunay, Erbil Karaman, Gülhan Güneş Elçi, Şerif Aksin, Barış Boza, Sena Sayan, Recep Yıldızhan, İsmet Alkış, Hanım Güler Şahin   +9 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Neurotoxicity of a Novel Local Anesthetic Agent, Ropivacaine: The Possible Roles of Bursts of Potential and Cytoplasmic Second Messenger

Journal of the Formosan Medical Association, 2007
Ropivacaine has been shown to induce convulsion following overdose or accidental intravenous injection, but the mechanisms are poorly understood.
Pei-Lin Lin, Shou-Zen Fan, Feng-Fong Tsai, Ming-Cheng Tsai, Chia-Hsien Lin, Chi-Hsiang Huang   +5 more
doaj   +1 more source

Studies on the Interception of the Pathways of Epileptic Convulsion Part III. Histological Studies on the Some Areas of Cat Diencephalon Concerning to intercept Epileptic Convulsion [PDF]

, 1959
The precise histological examination revealed that the area, of which selectiv damaging intercepted the epileptic convulsion, corresponded to the bilateral small spherical regions having a diameter of 2-3mm with H(2) of Forel's field as its center.
Kanbayashi, Tsuneo
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source