Results 131 to 140 of about 82,230 (340)

Comparative Study of Magnesium Sulfate and Phenytoin in Prevention of Convention in Pre-Eclamptic Patients

open access: yesپزشکی بالینی ابن سینا, 1999
Pre-eclampsia is one of the common complications in pregnancy and it is one of three causes of maternal mortality. The major cause of death in pre-eclampsia is adding convulsion and change to eclampsia.
Soghra Rabiei, Nadereh Behtash
doaj  

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Effects of sociodemographic factors on febrile convulsion prevalence

open access: yes, 2008
Background: The aim of the present study was to determine the lifetime risk (LTR) of febrile convulsion and the effects of socioeconomic factors affecting this risk among school children in Izmir province ...
Ergor, Alp   +5 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

The Critical Role of CT Imaging in Detecting Acute Neurological Complications of Eclampsia: A Case Series

open access: yesObgynia
Introduction: An intracranial hemorrhage (ICH) is a rare condition but potentially life-threatening event, especially in pregnancy, and could happen in patients with eclampsia.
Ayu Angelina Ronosulistyo   +6 more
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Experimental Study on Inhibition of the ep-Mouse Convulsion Part 4 Influence of Adrenal Glands and Genital Glands on the ep-Mouse Convulsion [PDF]

open access: yes, 1962
An attempt was made to study the influence of unilateral or bilateral adrenectomy of the ep-mouse, exchange transplantation of a pair of adrenal glands between the ep-mouse and the normal mouse followed by the successive administration of the adrenal ...
Kasahara, Junzi
core  

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