Results 41 to 50 of about 599,130 (347)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Zhileng xuebao, 2021 Considering the shortcomings of temperature and humidity-independent control in small and medium-scale residential and office buildings, a novel water chiller/heater based on dual evaporation temperatures was developed.
Li Zhao +5 more
doaj
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Applied Sciences, 2021 In a field test of a hybrid desiccant cooling system (HDCS) linked to a gas engine cogeneration system (the latter system is hereafter referred to as the combined heat and power (CHP) system), in the cooling operation mode, the exhaust heat remained and ...
Ji Hyeok Kim, Joon Ahn
doaj +1 more source
A Fresnel lenses based concentrated PV system in a greenhouse [PDF]
, 2011 The scope of this investigation is the development and testing of a new type of greenhouse with an integrated linear Fresnel lens, receiver module and an innovative system for tracking to exploit all direct radiation in a solar energy system.
Gieling, T.H. +4 more
core +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
AlgorithmsThe growing need for cooling, combined with the environmental concerns surrounding conventional mechanical vapour compression (MVC) systems, has accelerated research for sustainable cooling solutions driven by low-grade heat.
Patricia Kwakye-Boateng +2 more
doaj +1 more source
A mathematical modelling of frost growth dynamics on a surface of fin-and-tube air cooler [PDF]
MATEC Web of Conferences, 2020 A mathematical model was developed to predict the performance characteristics of fin-and-tube air coolers with plane fins, taking into account the temperature and humidity conditions, non-uniform thickness of the frost layer along the heat exchanger core,
Marinyuk Boris T. +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source