Results 31 to 40 of about 1,164,350 (247)

Heating and cooling of magnetars with accreted envelopes

open access: yes, 2009
We study the thermal structure and evolution of magnetars as cooling neutron stars with a phenomenological heat source in an internal layer. We focus on the effect of magnetized (B > 10^{14} G) non-accreted and accreted outermost envelopes composed of ...
A. D. Kaminker   +69 more
core   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Heating and cooling system [PDF]

open access: yes, 1982
A heating and cooling apparatus capable of cyclic heating and cooling of a test specimen undergoing fatigue testing is discussed. Cryogenic fluid is passed through a block clamped to the speciment to cool the block and the specimen.
Gardner, M. R., Imig, L. A.
core   +1 more source

The failure of stellar feedback, magnetic fields, conduction, and morphological quenching in maintaining red galaxies [PDF]

open access: yes, 2018
The quenching "maintenance'" and related "cooling flow" problems are important in galaxies from Milky Way mass through clusters. We investigate this in halos with masses $\sim 10^{12}-10^{14}\,{\rm M}_{\odot}$, using non-cosmological high-resolution ...
Chan, T. K.   +8 more
core   +2 more sources

Effectiveness of hand cooling and a cooling jacket on post‐exercise cooling rates in hyperthermic athletes [PDF]

open access: yesEuropean Journal of Sport Science, 2018
AbstractThis study compared the effects of a hand cooling glove (∼16°C water temperature; subatmospheric pressure of −40 mmHg) and a cooling jacket (CJ) on post‐exercise cooling rates (gastrointestinal core temperature, Tc; skin temperature, Tsk) and cognitive performance (the Stroop Colour–Word test). Twelve male athletes performed four trials (within
Tessa Maroni   +7 more
openaire   +3 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Paramagnetic Meissner Effect in Multiply-Connected Superconductors

open access: yes, 2000
We have measured a paramagnetic Meissner effect in Nb-Al2O3-Nb Josephson junction arrays using a scanning SQUID microscope. The arrays exhibit diamagnetism for some cooling fields and paramagnetism for other cooling fields.
A. B. Cawthorne   +31 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

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