Results 31 to 40 of about 343,593 (316)

Influence of a railway station and the Yangtze River on the local urban thermal environment of a subtropical city

open access: yesJournal of Asian Architecture and Building Engineering, 2022
Urbanization causes various climate-related environmental problems, such as the urban heat island phenomenon and extreme weather. As such, the outdoor thermal environment is worsening in cities, and researchers are increasingly concerned with mitigation ...
Qinli Deng   +3 more
doaj   +1 more source

Local Heat Transfer Measurements on a Rotating Flat Blade Model with a Single Film Hole [PDF]

open access: yes, 2009
An experimental study was performed to measure the heat transfer coefficient distributions on a flat blade model under rotating operating conditions. A steady-state thermochromic liquid crystal technique was employed to measure the surface temperature ...
Tao, Zhi   +8 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Full Coverage Discrete Hole Wall Cooling: Cooling Effectiveness [PDF]

open access: yesVolume 4: Heat Transfer; Electric Power, 1984
The development of a test facility for investigating full coverage discrete hole wall cooling for gas turbine combustion chamber wall cooling is described. A low temperature test condition of 750K mainstream temperature and 300K coolant temperature was used to investigate the influence of coolant flow rate at a constant cross flow Mach number ...
G.E. Andrews, M.L. Gupta, M.C. Mkpadi
openaire   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Unparticle effects in supernovae cooling

open access: yesPhysical Review D, 2007
Recently H. Georgi suggested that a scale invariant unparticle ${\mathcal{U}}$ sector with an infrared fixed point at high energy can couple with the SM matter via a higher-dimensional operator suppressed by a high cut-off scale. Intense phenomenological search of this unparticle sector in the collider and flavour physics context has already been made.
openaire   +2 more sources

Improvement of summer comfort by passive cooling with increased ventilation and night cooling [PDF]

open access: yes, 2013
The study describes the potential improvement of summer comfort and reduction of energy consumption that can be achieved by adopting passive cooling solutions, such as daytime comfort ventilation with increased air velocities and night cooling, in ...
Pellegrini, Tommaso
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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