Results 61 to 70 of about 17,091,673 (331)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

New physical principles of contact thermoelectric cooling

open access: yes, 2002
We suggest a new approach to the theory of the contact thermoelectric cooling (Peltier effect). The metal-metal, metal-n-type semiconductor, metal-p-type semiconductor, p-n junction contacts are analyzed.
Giraldo, J.   +3 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Unparticle effects in supernovae cooling

open access: yesPhysical Review D, 2007
Recently H. Georgi suggested that a scale invariant unparticle ${\mathcal{U}}$ sector with an infrared fixed point at high energy can couple with the SM matter via a higher-dimensional operator suppressed by a high cut-off scale. Intense phenomenological search of this unparticle sector in the collider and flavour physics context has already been made.
openaire   +2 more sources

Active cool roof effect: impact of cool roofs on cooling system efficiency

open access: yesAdvances in Building Energy Research, 2013
Cool roofs represent an acknowledged, relatively simple, and low-cost strategy to reduce cooling energy demand of buildings and mitigate urban heat island phenomena. The purpose of this paper is to study the coupled passive–active effect produced by such a technology, where the active effect consists of the cool roof capability to decrease the suction ...
PISELLO, ANNA LAURA   +2 more
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

A simulation of film cooling in the leading edge region of a turbine blade (trench effect on film effectiveness from cylinder in crossflow) [PDF]

open access: yes, 2012
Film cooling is one of the cooling system techniques applied to the turbine blade. Gas turbine use film cooling technique to protect turbine blade from expose directly to a hot gas to avoid the blade from defect.
Pairan, Mohamad Rasidi
core  

Sympathetic Cooling of Mixed Species Two-Ion Crystals for Precision Spectroscopy [PDF]

open access: yes, 2012
Sympathetic cooling of trapped ions has become an indispensable tool for quantum information processing and precision spectroscopy. In the simplest situation a single Doppler-cooled ion sympathetically cools another ion which typically has a different ...
D. J. Wineland   +10 more
core   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Intermittent Pringle maneuver may be beneficial for radiofrequency ablations in situations with tumor-vessel proximity

open access: yesInnovative Surgical Sciences, 2018
Radiofrequency ablation (RFA) represents a treatment option for non-resectable liver malignancies. Larger ablations can be achieved with a temporary hepatic inflow occlusion (Pringle maneuver – PM).
Poch Franz G.M.   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy