Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
NUMERICAL STUDY ON COOLING EFFECT POTENTIAL FROM VAPORIZER DEVICE OF LPG VEHICLE [PDF]
Over fuel consumption and increased exhaust gas due to the A/C system have become a serious problem. On the other hand, the LPG-fueled vehicle provides potential cooling from LPG phase changes in the vaporizer.
MUJI SETIYO +4 more
doaj
SPG4 and Dementia: Expanding the Clinical Spectrum
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source
Combined Thermal Effect of Cool Roof and Cool Façade on a Prototype Building
AbstractRecently, huge efforts were made to develop new passive solutions for optimizing building summer thermal-energy behavior. While cool roofs are well investigated, a lack of knowledge is detected about the benefits deriving from the combination of cool roofs and cool façades.
PISELLO, ANNA LAURA +4 more
openaire +4 more sources
Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer +11 more
wiley +1 more source
Numerical Study on Cooling Effect of Downhole Cooling System of Instrument While Drilling
Deep and ultra-deep reservoirs have been listed as important replacement areas for oil and gas resources. However, downhole high temperature in deep layers shortens the service life of the instrument while drilling, and even makes it fail.
Liu Ke +3 more
doaj
Enhancement of Cooling Effectiveness with Mist Assisted Film Cooling
info:eu-repo/semantics ...
Biswal, Pratibha +2 more
openaire +2 more sources
Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar +3 more
wiley +1 more source
Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs +7 more
wiley +1 more source

