Results 31 to 40 of about 63,450 (264)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Unparticle effects in supernovae cooling
Physical Review D, 2007 Recently H. Georgi suggested that a scale invariant unparticle ${\mathcal{U}}$ sector with an infrared fixed point at high energy can couple with the SM matter via a higher-dimensional operator suppressed by a high cut-off scale. Intense phenomenological search of this unparticle sector in the collider and flavour physics context has already been made.
openaire +2 more sources
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
BuildingsIndoor environments have received increasing attention in recent years, and achieving high-quality indoor conditions has become increasingly important. Underfloor air distribution (UFAD) systems have attracted significant interest due to their potential ...
Yen-Chin Wu +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Environmental Research: ClimateExtreme heat is projected to increase in frequency and intensity. Commonly applied infrastructure-based urban heat mitigation strategies, including greenery and reflective materials, have the potential to reduce heat exposure.
Sara V Hesse +4 more
doaj +1 more source
Energies, 2023 Modern gas turbines have evolved by increasing the turbine inlet temperature (TIT) to improve performance. This development has led to a demand for cooling techniques.
Seokmin Kim +3 more
doaj +1 more source
Full Coverage Discrete Hole Wall Cooling: Cooling Effectiveness [PDF]
Volume 4: Heat Transfer; Electric Power, 1984 The development of a test facility for investigating full coverage discrete hole wall cooling for gas turbine combustion chamber wall cooling is described. A low temperature test condition of 750K mainstream temperature and 300K coolant temperature was used to investigate the influence of coolant flow rate at a constant cross flow Mach number ...
G.E. Andrews, M.L. Gupta, M.C. Mkpadi
openaire +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source