Results 91 to 100 of about 9,964,947 (304)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Multilateral cooperation in the Post-Soviet space

open access: yes, 2023
openIn the thesis, I am exploring the multilateral and bilateral cooperation between the Post-Soviet countries starting from the collapse until the present day.
YDYRYSOVA, AEMILIA
core  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

New EC quarterly on fisheries cooperation

open access: yes, 2014
bilingual quarterly 'EC Fisheries Cooperation Bulletin/ CE Cooperation Peche' Copies can be obtained, free of charge, from: Cornelia E Nauen EC Fisheries Cooperation Bulletin Commission of the European Communities DG VIII/B/5 - 200 rue de ...
Technical Centre for Agricultural and Rural Cooperation
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Cooperation for Innovation in Payment Systems: The Case of Mobile Payments [PDF]

open access: yes
In this paper, we provide a definition of mobile payments and we analyze the markets that could be targeted by mobile payment service providers, both in developed and in developing countries. Focusing on the case of developed countries, we introduce five
Marianne VERDIER, Marc BOURREAU
core  

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

Cooperation in the development of free software projects

open access: yesRevista Ingenio, 2014
This article presents a set of elements for cooperation pertinent to free software projects and cooperation theories, based on recognizing how geographically distributed developers in the world find the motivation to create a community around free ...
Byron Cuesta Quintero   +1 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Influence Mechanism of Droplet Re-Entrainment in Wire Mesh Filter for Marine Gas Turbine

open access: yesShanghai Jiaotong Daxue xuebao
The re-entrainment of droplets in the inlet filtration components of marine gas turbines severely affects the gas intake quality and the safe operation of gas turbines.
FEI Yunda, LIU Yanming, WANG Jianhua, SUN Shijun
doaj   +1 more source

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