Results 81 to 90 of about 9,964,947 (304)

An Asia-Pacific Model of Development Cooperation [PDF]

Part One of the Osaka Action Agenda has clarified the implications of the basic political commitment to free and open trade and investment in the Bogor Declaration and has set out operational guiding principles and a well-developed strategy of ...
Foundation for Development Cooperation
core   +2 more sources

A Body–Machine Interface for Assistive Robot Control in Spinal Cord Injury: System Description and Preliminary Tests

Applied Sciences
Motor impairments, particularly spinal cord injuries, impact thousands of people each year, resulting in severe sensory and motor disabilities. Assistive technologies play a crucial role in supporting these individuals with activities of daily living ...
Aurora Freccero, Maddalena Feder, Giorgio Grioli, Manuel Giuseppe Catalano, Antonino Massone, Antonio Bicchi, Maura Casadio   +6 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Development of a Whole Body Motion Support Type Mobile Suit and Evaluation of Cerebral Activity Corresponding to the Cortical Motor Areas

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2013
We developed a new whole body motion support type mobile suit. This suit can be used separately for supporting the upper and/or lower limbs, for assisting in ADL (Activities of Daily Living).
Eiichirou TANAKA, Shozo SAEGUSA, Louis YUGE   +2 more
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Resource supply and the evolution of public-goods cooperation in bacteria [PDF]

, 2008
This work was funded by the Wellcome Trust VIP scheme (administered by the University of Liverpool Research Development Fund), the Leverhulme Trust and the Royal Society.
Dan Racey, Racey, Dan, Racey Dan, Racey, Dan A., Gardner, A, Brockhurst, Michael A.; id_orcid, Buckling Angus, Brockhurst, MA, Michael A Brockhurst, Angus Buckling, Gardner Andy, Gardner, Andy, Brockhurst, Michael A., Andy Gardner, Brockhurst Michael A, Buckling, Angus, Buckling, A, Racey, D, Brockhurst, Michael A   +18 more
core   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

A meta-model for cooperation systems

, 2022
S.239-246Today's enterprise information and cooperation systems are numerous and diverse. Users have problems of information overload, task interruption and media discontinuity.
Jeners, N., Prinz, W., Franken, S.
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source