Results 61 to 70 of about 1,768,532 (298)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

A Formal Framework for Modeling Trust and Reputation in Collective Adaptive Systems [PDF]

, 2016
Trust and reputation models for distributed, collaborative systems have been studied and applied in several domains, in order to stimulate cooperation while preventing selfish and malicious behaviors. Nonetheless, such models have received less attention
Aldini, Aldini, Aldini, Alessandro Aldini, Beth, Bortolussi, Cardelli, Cho, Ganeriwal, Goguen, Han, He, Jøsang, Kamvar, Kim, Kwiatkowska, L. Vissat, Li, Li, Marmol, Maurice H. ter Beek, Michele Loreti, Momani, Mousa, Ngai, Packer, Reith, Tarable, ter Beek, Xiong, Yaich, Yu, Zhang, Zhou   +33 more
core   +3 more sources

Remote Sensing Small Object Detection Network Based on Multi-Scale Feature Extraction and Information Fusion

Remote Sensing
Nowadays, object detection algorithms are widely used in various scenarios. However, there are further small object detection requirements in some special scenarios.
Junsuo Qu, Tong Liu, Zongbing Tang, Yifei Duan, Heng Yao, Jiyuan Hu   +5 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Simultaneous light emission and detection of an AlGaInP quantum well diode

AIP Advances, 2023
When a quantum well (QW) diode is biased with a forward voltage and illuminated with an external shorter-wavelength light, the device simultaneously emits and detects light, with the injected current and the induced current mixed inside the wells ...
Ziqi Ye, Hao Zhang, Xumin Gao, Kang Fu, Haibo Zeng, Yuhuai Liu, Yongjin Wang, Hiroshi Amano   +7 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Interference Mitigation Through Limited Receiver Cooperation: Symmetric Case

, 2009
Interference is a major issue that limits the performance in wireless networks, and cooperation among receivers can help mitigate interference by forming distributed MIMO systems.
Tse, David N. C., Wang, I-Hsiang
core   +2 more sources

Mechanism of CO2 Emission Reduction by Global Energy Interconnection

Global Energy Interconnection, 2018
The challenge of global warming has become a driving force for a global energy transition. The Global Energy Interconnection (GEI) is a modern energy system aimed at meeting the global power demand in a clean and green manner.
Yuanbing Zhou, Xing Chen, Xin Tan, Changyi Liu, Shining Zhang, Fang Yang, Wenji Zhou, Han Huang   +7 more
doaj   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source