Results 71 to 80 of about 872,356 (317)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

ASSESSMENT OF GENDER ACCESS TO AGRICULTURAL LOANS FROM COOPERATIVE SOCIETIES IN DEKINA LOCAL GOVERNMENT AREA OF KOGI STATE, NIGERIA

open access: yesJournal of Asian Rural Studies, 2017
This study assessed gender access to agricultural loans from cooperative societies in Dekina Local Government Area of Kogi State, Nigeria. Primary data used were collected from 160 registered cooperative members in the study area.
Adejo P.E, Adejo E.G, Shaibu U.M
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Non-permanence for three-species Lotka-Volterra cooperative difference systems

open access: yesAdvances in Difference Equations, 2017
The permanence for three-species cooperative difference systems of Lotka-Volterra is considered. By constructing some suitable regions, we prove that a cooperative system cannot be permanent.
Guichen Lu, Zhengyi Lu
doaj   +1 more source

Virginia Cooperative Extension Pledge Form

open access: yes, 2014
This is a two page gift/pledge form in support of Virginia Cooperative ...

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Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

MATCHING CONFIGURATIONS PROJECTS OF COOPERATIVE MILK COLLECTION PROJECT ENVIRONMENT

open access: yesВісник Національного технічного університету «ХПÌ». Серія: Стратегічне управління, управління портфелями, програмами та проектами, 2017
The condition analysis of dairy farming is done and the reasons for its degradation are revealed. The need of technologically integrated production systems projects, harvesting, and processing of milk are substantiated.
Анатолій Миколайович ТРИГУБА   +3 more
doaj   +1 more source

Field Crops PMG ' Insect control, 2021

open access: yes, 2021
This is a chapter of the 2021 Field Crops PMG. The Virginia Pest Management Guide (PMG) series lists options for management of major pests: diseases, insects, nematodes, and weeds.
Taylor, Sally V., Laub, Curtis A.
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Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Virginia Cooperative Extension Organizational Chart

open access: yes, 2019
This document is an organizational chart of Virginia Cooperative Extension personnel.title from VCE publications page; document revised July ...
Jones, Edwin J.
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