Results 91 to 100 of about 2,392,581 (306)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
, 2001 We study two forms of a symmetric cooperative game played by three players, one classical and other quantum. In its classical form making a coalition gives advantage to players and they are motivated to do so. However in its quantum form the advantage is
Iqbal, A., Toor, A. H.
core +3 more sources
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Catch Shares in Action: Mexican Vigía Chico Cooperative Spiny Lobster Territorial Use Rights for Fishing Program [PDF]
, 2013 The Mexican Pescadores de Vigía Chico Cooperative is a group-allocated, area-based catch share that manages the Punta Allen spiny lobster fishery. The catch share, or Territorial Use Rights for Fishing (TURF) program, includes a number of special design ...
Erica Cunningham
core
Spreading speeds and traveling waves for non-cooperative reaction-diffusion systems
, 2010 Much has been studied on the spreading speed and traveling wave solutions for cooperative reaction-diffusion systems. In this paper, we shall establish the spreading speed for a large class of non-cooperative reaction-diffusion systems and characterize ...
Wang, Haiyan
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Multi-Agent Reinforcement Learning Based Cooperative Content Caching for Mobile Edge Networks
IEEE Access, 2019 To address the drastic growth of data traffic dominated by streaming of video-on-demand files, mobile edge caching/computing (MEC) can be exploited to develop intelligent content caching at mobile network edges to alleviate redundant traffic and improve ...
Wei Jiang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source