Results 91 to 100 of about 177,076 (305)
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Manager Power, Member Behavior and Capital Structure: Portuguese Douro Wine Cooperatives [PDF]
Leverage is one of the most important financial factors to the survival and viability of agricultural cooperatives (e.g., wine cooperatives) during a period of intense competition.
Caldas, Jose Vaz +2 more
core +1 more source
Weight control follow-up - March [PDF]
Consists of information on weight control, diet, exercise, and behavior modification.
Taper, L. Janette
core
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Weight control follow-up - February [PDF]
Consists of information on weight control, diet, exercise, and behavior modification.
Taper, L. Janette
core
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
AGRICULTURAL COOPERATIVE MANAGERS AND THE BUSINESS ENVIRONMENT [PDF]
Managers of agricultural cooperatives were contacted to determine their knowledge/capabilities and perspectives of the cooperative environment with special emphasis given to the importance of cooperative principles to the operation and success of the ...
Green, Thomas Wade, Adrian, John L., Jr.
core +1 more source
Weight control follow-up - April [PDF]
Consists of information on weight control, diet, exercise, and behavior modification.
Taper, L. Janette
core +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Cooperative Strategies in Groups of Strangers: An Experiment [PDF]
We study cooperation in four-person economies of indefinite duration. Subjects interact anonymously playing a prisoner’s dilemma. We identify and characterize the strategies employed at the aggregate and at the individual level.
Marco Casari +2 more
core

