Results 81 to 90 of about 4,612,230 (303)
Virginia Cooperative Extension Organizational Chart
, 2019 This document is an organizational chart of Virginia Cooperative Extension personnel.title from VCE publications page; document revised July ...
Jones, Edwin J.
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Values, ethics and empowering the self through cooperative education [PDF]
, 2011 Following the recent global financial crisis and the collapse of major organisations such as Lehman Brothers, and the earlier corporate failings of Enron and HIH, there has been a shift of focus towards the role of ethics education in the formation of ...
Campbell, Matthew, Zegwaard, Karsten E.
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Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Virginia Cooperative Extension Organizational Chart
, 2017 This document is an organizational chart of Virginia Cooperative Extension personnel.title from VCE publications page; document revised August ...
Jones, Edwin J.
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Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Multi-robot Voronoi tessellation based area partitioning algorithm study
Paladyn, 2018 This article is focused on the multi-robot applied Voronoi tessellation based area partitioning algorithm operation and properties. The selection of main parameters of the algorithm is covered and explanation of the algorithm functionality is given.
Alexandrov Vladimir +2 more
doaj +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Effects of strategy-relationship coevolution on the emergence of cooperation in multilayer networks
Frontiers in PhysicsSince social interactions are inherently embedded in multiple relational contexts, single-network models often fall short in explaining the evolution of cooperation.
Mengmeng Liu
doaj +1 more source
Virginia Cooperative Extension Volunteers: Extending Knowledge and Improving Lives
, 2015 This publication reviews the volunteer screening process for the Virginia Cooperative ...
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USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source