Results 61 to 70 of about 874,631 (295)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Animal Behavior: Tolerant Primates Cooperate Best [PDF]

open access: yesCurrent Biology, 2007
Chimpanzees and bonobos show different cooperative tendencies when the prize is easily monopolizable food: bonobos cooperate more than their less socially tolerant relatives.
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The relationship between the interactive behavior of industry–university–research subjects and the cooperative innovation performance: The mediating role of knowledge absorptive capacity

open access: yesFrontiers in Psychology, 2023
IntroductionIndustry–university–research cooperation innovation, which is often characterized by resource complementarity and the sharing technology, has become one of the most preferred innovation cooperation methods for enterprises.
Xiulan Meng   +7 more
doaj   +1 more source

Collective periodicity in mean-field models of cooperative behavior

open access: yes, 2015
We propose a way to break symmetry in stochastic dynamics by introducing a dissipation term. We show in a specific mean-field model, that if the reversible model undergoes a phase transition of ferromagnetic type, then its dissipative counterpart ...
Collet, Francesca   +2 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Identifying Strategies for Implementing Multi-Generational Gravity in Hospitals of Hamadan University of Medical Sciences [PDF]

open access: yesRāhburdhā-yi Mudīriyyat dar Niẓām-i Salāmat
Background: Generational differences in today's work environments, especially in hospitals, can affect organizational interactions, employee motivation, and the effectiveness of health services.
Samaneh Zarin Khalili   +4 more
doaj  

Contagion of Cooperation in Static and Fluid Social Networks. [PDF]

open access: yesPLoS ONE, 2013
Cooperation is essential for successful human societies. Thus, understanding how cooperative and selfish behaviors spread from person to person is a topic of theoretical and practical importance.
Jillian J Jordan   +4 more
doaj   +1 more source

Fluctuation driven fixation of cooperative behavior [PDF]

open access: yesBiosystems, 2015
Cooperative behaviors are defined as the production of common goods benefitting all members of the community at the producer's cost. They could seem to be in contradiction with natural selection, as non-cooperators have an increased fitness compared to cooperators.
openaire   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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