Results 31 to 40 of about 93,282 (260)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Channel-Aware Energy-Efficient Two-Hop Cooperative Routing Protocol for Underwater Acoustic Sensor Networks

IEEE Access, 2019
This paper sought to investigate the performance of multi-hop underwater acoustic sensor networks (UW-ASNs) when they deploy cooperative routing algorithms combining the cooperative communication and routing methods. Taking into account energy efficiency,
Hoa Tran-Dang, Dong-Seong Kim
doaj   +1 more source

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Controlled Power Cooperative Non Orthogonal Multiple Access Relay Networks

Electrica
Recent work related to cooperative communication and power allocation has attracted much attention among researchers. This paper compares orthogonal multiple access (OMA), non orthogonal multiple access (NOMA), and cooperative NOMA.
Mario Ligwa, Vipin Balyan
doaj   +1 more source

Performance Analysis of Wireless Cooperative Networks with Iterative Incremental Relay Selection [PDF]

AUT Journal of Electrical Engineering, 2017
In this paper, an iterative incremental relay selection (IIRS) scheme is considered for wireless cooperative networks in order to increase the reliability of transmission.
S. Poursajadi, M. H. Madani
doaj   +1 more source

COOPERATION WITHOUT COMMUNICATION [PDF]

, 1988
Intelligent agents must be able to interact even without the benefit of communication. In this paper we examine various constraints on the actions of agents in such situations and discuss the effects of these constraints on their derived utility. In particular, we define and analyze basic rationality; we consider various assumptions about independence;
Michael R. Genesereth, Matthew L. Ginsberg, Jeffrey S. Rosenschein   +2 more
openaire   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Joint time and power allocation for uplink cooperative non-orthogonal multiple access based massive machine-type communication Network

International Journal of Distributed Sensor Networks, 2018
Non-orthogonal multiple access is an essential promising solution to support large-scale connectivity required by massive machine-type communication scenario defined in the fifth generation (5G) mobile communication system.
Shujun Han, Xiaodong Xu, Litong Zhao, Xiaofeng Tao   +3 more
doaj   +1 more source