Results 91 to 100 of about 27,014 (309)

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

open access: yesAdvanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda   +8 more
wiley   +1 more source

Cooperative Games with Incomplete Information: Some Open Problems [PDF]

open access: yes
This is a brief survey describing some of the recent progress and open problems in the area of cooperative games with incomplete information. We discuss exchange economies, cooperative Bayesian games with orthogonal coalitions, and issues of cooperation ...
Roberto Serrano, Francoise Forges
core  

Consensus Formation and Change are Enhanced by Neutrality

open access: yesAdvanced Science, EarlyView.
Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag   +3 more
wiley   +1 more source

Finite Geometric Spaces, Steiner Systems and Cooperative Games

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2014
Some relations between finite geometric spaces and cooperative games are considered. The games associated to Steiner systems, in particular projective and affine planes, are considered. The properties of winning and blocking coalitions are investigated.
Maturo Antonio, Maturo Fabrizio
doaj   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

open access: yesAdvanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su   +10 more
wiley   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

open access: yesAdvanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du   +4 more
wiley   +1 more source

Pricing and Advertising Decisions in a Three-level Supply Chain with Nash, Stackelberg and Cooperative Games

open access: yesInternational Journal of Industrial Engineering and Production Research, 2016
Pricing and advertising are two important marketing strategies in the supply chain management which lead to customer demand’s increase and therefore higher profit for members of supply chains. This paper considers advertising, and pricing decisions
Parinaz Esmaeili   +2 more
doaj  

Cooperative weakest link games

open access: yesInternational Joint Conference on Autonomous Agents and Multiagent Systems, 2014
We introduce Weakest Link Games (WLGs), a cooperative game modeling domains where a team's value is determined by its weakest member. The game is represented as an edge-weighted graph with designated source and target vertices, where agents are the edges. The quality of a path between the source vertex and target vertex is the minimal edge weight along
Bachrach, Yoram   +4 more
openaire   +3 more sources

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