Results 271 to 280 of about 8,353 (338)

A novel NLP-based method and algorithm to discover RNA-binding protein (RBP) motifs, contexts, binding preferences, and interactions. [PDF]

RNA
Elhajjajy SI, Weng Z.
europepmc   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Metagenomic analysis of antimicrobial resistance, virulence, and mobile genetic elements in the gut microbiota of Caprinae species. [PDF]

Commun Biol
Su JW, Elsheikha HM, Guo L, Liu R, Shang KM, Yu HL, Ma H, Ni HB, Chen BN, Zhang XX, Yang X.   +10 more
europepmc   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

Advanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu, Ting Wang, Jietao Liu, Jiacheng Qin, Bin Yang, Yihang Liu, Pengfei Li, Gaoxue Wang, Fei Ling   +8 more
wiley   +1 more source

Feasibility, challenges, and solutions for implementing targeted universal tuberculosis testing: perceptions of healthcare professionals in South Africa. [PDF]

BMC Health Serv Res
Motlhaoleng K, Maartens G, Vilakazi-Nhlapo K, Golub JE, Shearer K.   +4 more
europepmc   +1 more source

A Hydrogen‐Releasing Nanozyme Engineers a Mitochondrial ROS Amplifier for Self‐Sustaining Catalytic Immunotherapy

Advanced Science, EarlyView.
We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi, Jingrui Cao, Tong Wu, Guang Yang, YaWen Yang, Shixin Zhang, Wenwen Su, Hongyu Chu, Yangyang Zhao, Shan Jiang, Qiong Wu, Dongxu Jiao, Fangfang Chen   +12 more
wiley   +1 more source

Cross-kingdom metabolic cooperation drives vanillic acid biosynthesis: A spatiotemporal dissection of microbial functional networks in solid-state fermentation. [PDF]

Curr Res Food Sci
Tong W, Qiao L, Yang Y, Li X, Zhang Y, Huang Z, Luo H, Zhao L, Zhang S.   +8 more
europepmc   +1 more source

Icariin shapes post-withdrawal fecal resistome dynamics in layer hens. [PDF]

J Anim Sci Biotechnol
Zhang J, Shi X, Peng S, Zhang C, Qiao S, Yu H.   +5 more
europepmc   +1 more source

A snapshot of Italian nursing homes for people with dementia: A national survey of 1671 facilities. [PDF]

J Alzheimers Dis
Vaccaro R, Lorenzini P, Giaquinto F, Matascioli F, Salvi E, Carnevale G, Locuratolo N, Vanacore N, Bacigalupo I, Permanent Table of the National Dementia Plan Study Group *, NHs Study Group *.   +10 more
europepmc   +1 more source

Competition and cooperation: The plasticity of bacterial interactions across environments. [PDF]

PLoS Comput Biol
Solowiej-Wedderburn J, Pentz JT, Lizana L, Schroeder BO, Lind PA, Libby E.   +5 more
europepmc   +1 more source