Results 41 to 50 of about 150,306 (264)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

PENERAPAN MODEL PEMBELAJARAN COOPERATIVE LEARNING TIPE COOPERATIVE INTEGRATED READING AND COMPOSITION (CIRC) UNTUK MENINGKATKAN RASA INGIN TAHU SISWA DALAM PEMBELAJARAN IPS. [PDF]

, 2016
Permasalahan yang timbul dari hasil pengamatan peneliti pada pembelajaran IPS di kelas VII H SMP Negeri 14 Bandung. Berdasarkan hasil observasi yang dilakukan oleh peneliti, peneliti melihat kurangnya rasa ingin tahu siswa dalam pembelajaran IPS. Hal ini
Yuniastuti, Nisa
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Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

PEMBELAJARAN MEMBANDINGKAN STRUKTUR TEKS CERPEN DENGAN TEKS ULASAN FILM DENGAN MENGGUNAKAN MODEL CIRC ( COOPERATIVE INTEGRATED READING AND COMPOSITION) PAD A SISWA KELAS XI SMA NEGERI 1 CIWIDEY TAHUN PELAJARAN 201 5 /201 6 [PDF]

, 2016
vi ABSTRAK Membandingkan adalah menilai atau memberikan penilaian terhadap dua objek atau lebih baik itu kelmahan ataupun kelebihan dari masing - masing objek tersbut .
IRFAN HILMAN MUFRODI, 1150301 69
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Using Cooperative Integrated Reading and Composition (CIRC) Technique in Teaching Reading Comprehension

IKHLAS: Jurnal Pengabdian Dosen dan Mahasiswa
The students have lack of the vocabulary, difficult to identify the main idea, supporting idea, factual information of the text and guessing meaning of the word. The purpose of this activity was to explain whether CIRC technique can better improve students’ reading comprehension and to identify the factors that influence the changing of students ...
null Syaifullah, null Asmirawati
openaire   +1 more source

Boosting Students’ Skimming Reading Skill by Using Cooperative Integrated Reading and Composition (CIRC) Learning Method

Journal of English Education and Social Science, 2022
The title of this thesis is Boosting students’ skimming reading skill by using Cooperative Integrated Reading and Composition (CIRC ) Learning Method (A Collaborative Classroom Action Research to the Second Year Students of SMAN 1 Samalanga). The researcher put two problems of this research with the questions as follow: first, how does CIRC method ...
null SULIHATI, null Misnawati
openaire   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

PEMBELAJARAN MENGANALISIS TEKS CERPEN DENGAN MENGGUNAKAN MODEL CIRC (COOPERATIVE INTEGRATED READING AND COMPOSITION) SEBAGAI UPAYA PENINGKATAN HASIL BELAJAR DAN KREATIVITAS PADA SISWA KELAS XI SMA PASUNDAN 7 BANDUNG TAHUN PELAJARAN 2017/2018 [PDF]

, 2017
Penelitian dengan judul “Pembelajaran Menganalisis Teks Cerpen Dengan Menggunakan Model CIRC (COOPERATIVE INTEGRATED READING AND COMPOSITION) sebagai Upaya Peningkatan Hasil Belajar dan Kreativitas pada Siswa Kelas XI SMA Pasundan 7 Bandung Tahun
EKA RAHMAWATI, 135030015
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Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

PEMBELAJARAN MENGANALISIS PESAN DARI SATU BUKU FIKSI (KUMPULAN CERPEN) DENGAN METODE COOPERATIVE INTEGRATED READING AND COMPOSITION (CIRC) UNTUK PEMBENTUKAN KARAKTER PADA PESERTA DIDIK KELAS XI SMKN 4 BANDUNG TAHUN AJARAN 2017/2018 [PDF]

, 2018
Metode Cooperative Integrated Reading and Composition (CIRC) adalah metode yang bertujuan untuk memperluas pengetahuan peserta didik khususnya dalam pembelajaran menganalisis pesan dari satu buku fiksi (kumpulan cerpen). Dengan demikian, penulis
RIFA ALIFFAH NUR ALFATAN, 145030017
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