Results 21 to 30 of about 41,414 (267)

IC2 participates in the cooperative activation of outer arm dynein densely attached to microtubules

Cell Structure and Function, 2023
Ciliary outer-arm dynein (OAD) consists of heavy chains (HCs), intermediate chains (ICs), and light chains (LCs), of which HCs are the motor proteins that produce force.
Yusuke Kondo, Tomoka Ogawa, Emiri Kanno, Masafumi Hirono, Takako Kato-Minoura, Ritsu Kamiya, Toshiki Yagi   +6 more
doaj   +1 more source

Noncovalent Bonds through Sigma and Pi-Hole Located on the Same Molecule. Guiding Principles and Comparisons

Molecules, 2021
Over the last years, scientific interest in noncovalent interactions based on the presence of electron-depleted regions called σ-holes or π-holes has markedly accelerated.
Wiktor Zierkiewicz, Mariusz Michalczyk, Steve Scheiner   +2 more
doaj   +1 more source

Interplay between Beryllium Bonds and Anion-π Interactions in BeR2:C6X6:Y− Complexes (R = H, F and Cl, X = H and F, and Y = Cl and Br)

Molecules, 2015
A theoretical study of the beryllium bonds in BeR2:C6X6 (R = H, F, Cl and X = H and F) has been carried out by means of MP2/aug′-cc-pVDZ computational methods. In addition, the ternary complexes BeR2:C6X6:Y− (Y = Cl and Br) have been analyzed. Geometric,
Marta Marín-Luna, Ibon Alkorta, José Elguero, Otilia Mó, Manuel Yáñez   +4 more
doaj   +1 more source

Sequencing and Cooperation [PDF]

Operations Research, 1994
In machine scheduling the first problem is to find a timetable that is optimal with respect to some efficiency criterion. If the jobs come from different clients the solution of the optimization problem is not the end of the story. In addition, we have to decide how the minimal total cost must be distributed among the parties involved.
Curiel, I., Potters, J.A.M., Rajendra Prasad, V., Tijs, S.H., Veltman, B.   +4 more
openaire   +6 more sources

Extra contribution to the crystal stability of insensitive explosive TATB: The cooperativity of intermolecular interactions

Defence Technology, 2023
An in-depth analysis on the cooperativity of intermolecular interactions including hydrogen bonding and π-π stacking in 1,3,5-triamino-2,4,6-trinitrobenzene (TATB) crystal was studied.
Zhi-xiang Zhang, Yi-tao Si, Tao Yu, Wei-peng Lai, Yi-ding Ma, Mao-chang Liu, Ying-zhe Liu, Bo-zhou Wang   +7 more
doaj   +1 more source

T‐495, a novel low cooperative M1 receptor positive allosteric modulator, improves memory deficits associated with cholinergic dysfunction and is characterized by low gastrointestinal side effect risk

Pharmacology Research & Perspectives, 2020
M1 muscarinic acetylcholine receptor (M1R) activation can be a new therapeutic approach for the treatment of cognitive deficits associated with cholinergic hypofunction. However, M1R activation causes gastrointestinal (GI) side effects in animals.
Takao Mandai, Yuu Sako, Emi Kurimoto, Yuji Shimizu, Minoru Nakamura, Makoto Fushimi, Ryouta Maeda, Maki Miyamoto, Haruhide Kimura   +8 more
doaj   +1 more source

Cooperative or Uncooperative Cooperatives? Digging into the Process of Cooperation in Food and Agriculture Cooperatives [PDF]

Journal of Agriculture, Food Systems, and Community Development, 2018
Cooperative organizing around food and agricul­ture is nothing new (Knupfer, 2013). However, there has been a recent resurgence of interest in the cooperative legal form. This research has followed this rebirth in a region in the western United States where rural producers and urban consumers, gentrifying communities of color, and environ­mentally ...
James Hale, Michael Carolan
openaire   +2 more sources

Single-molecule methods for characterizing receptor dimers reveal metastable opioid receptor homodimers that induce functional modulation

Nature Communications
Opioid receptors (ORs) are critical for endogenous and synthetic analgesics. OR homodimerization is considered important for their pharmacological diversity, but whether they form homodimers remains controversial.
Peng Zhou, Taka A. Tsunoyama, Rinshi S. Kasai, Koichiro M. Hirosawa, Ziya Kalay, Amine Aladag, Takahiro K. Fujiwara, Tatsushi Yokoyama, Masayuki Sakamoto, Ryoji Kise, Masataka Yanagawa, Asuka Inoue, Simone Pigolotti, Akihiro Kusumi   +13 more
doaj   +1 more source

Cooperation and wealth [PDF]

Journal of Economic Behavior & Organization, 2004
We calculate the equilibrium fraction of cooperators in a population in which payoffs accrue from playing a single-shot prisoner's dilemma game. Individuals who are hardwired as cooperators or defectors are randomly matched into pairs, and cooperators are able to perfectly find out the type of a partner to a game by incurring a recognition cost.
Stark, Oded, Stark, Oded
openaire   +5 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source