Results 111 to 120 of about 116,296 (308)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Coordinate Questions in the Web Environment

open access: yes, 2014
This article contributes to the clarification of the coordinate reference systems (CRS) used by some Web mapping appli- cations. This is a complex issue, mainly because of a lack of pertinent information; there is little published literature on CRS, and ...
FAVRETTO, ANDREA
core   +1 more source

Mapping the colon through the colonoscope’s coordinates – The Copenhagen Colonoscopy Coordinate Database

open access: yesScientific Data
Colonoscopy is the leading endoscopic technique when it comes to implementing artificial intelligence-based tools to optimize the procedure. However, no database consisting of the colonoscope's coordinates exists, allowing for a mapping with timestamps of the colonoscope path through the colon.
Kristoffer Mazanti Cold   +8 more
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

CPR: Crossbar-grain Pruning for an RRAM-based Accelerator with Coordinate-based Weight Mapping

open access: yes, 2022
Resistive random access memory (RRAM)-based crossbar arrays with the process-in-memory (PIM) approach are emerging as a promising technique for accelerating deep neural networks (DNNs) with their high-speed and multi-level programming characteristics ...
Park, Jihye, Kang, Seokhyeong
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

The curvature coordinate system

open access: yes, 2007
The paper describes a concept for a curvature coordinate system on regular curved surfaces from which faceted surfaces with plane quadrangular facets can be designed. The lines of curvature are used as parametric lines for the curvature coordinate system
Almegaard, Henrik
core  

A neural hysteresis model for magnetostrictive sensors and actuators

open access: yesInternational Journal of Advanced Robotic Systems, 2016
In this article, a constraint factor is introduced into the hysteretic operator so that the hysteretic operator can pass through the origin in every minor coordinate system. Based on the hysteretic operator, an expanded input space is constructed.
Lianwei Ma   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

On Dimensionality of Coordinate-Based Network Distance Mapping

open access: yes, 2005
In this paper, we investigate the veracity of a basic premise, “that network distance is Euclidean”, assumed in a class of recently proposed techniques that embed Internet hosts in a Euclidean space for the purpose of estimating the delay or “distance ...
Lee, Sanghwan   +3 more
core  

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