Results 71 to 80 of about 3,739,334 (352)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Designs for thermal harvesting with nonlinear coordinate transformation

AIP Advances, 2018
In this paper a thermal concentrating design method was proposed based on the concept of generating function without knowing the needed coordinate transformation beforehand.
Qingxiang Ji, Guodong Fang, Jun Liang
doaj   +1 more source

Analytical dual quaternion algorithm of the weighted three-dimensional coordinate transformation [PDF]

, 2022
Huaien Zeng, Junjie Wang, Zhihao Wang, Siyang Li, Haiqing He, Guobin Chang, Ronghua Yang   +6 more
openalex   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Autonomous navigation system [PDF]

, 1981
An inertial navigation system utilizing a servo-controlled two degree of freedom pendulum to obtain specific force components in the locally level coordinate system is described.
Merhav, S. J.
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Least squares support vector machine model for coordinate transformation

Geodesy and Cartography, 2019
In coordinate transformation, the main purpose is to provide a mathematical relationship between coordinates related to different geodetic reference frames. This gives the geospatial professionals the opportunity to link different datums together. Review
Yao Yevenyo Ziggah, Youjina Hu, Yakubu Issaka, Prosper Basommi Laari   +3 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

A non-reflecting metamaterial slab under the finite-embedded coordinate transformation

, 2010
From the explicit solutions of Maxwell's equations under the coordinate transformation, the conditions for non-reflecting boundaries for the two-dimensionally propagating light waves, in a finite-embedded coordinate transformation metamaterial slab are ...
Bergamin, Byoungho Lee, Chen, Cummer, Gallina, Il-Min Lee, Kundtz, Kyoung-Youm Kim, Lai, Li, Pendry, Rahm, Rahm, Rahm, Schurig, Seung-Yeol Lee, Ward, Zhang   +17 more
core   +1 more source