Results 71 to 80 of about 4,047,721 (330)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Applied SciencesWith strong technology improvement, especially GNSS, coordinate transformation has become an essential tool in everyday practice. For this reason, it is beneficial to have a good understanding of the mathematical process of coordinate transformation, as ...
Tedi Banković +3 more
doaj +1 more source
International Journal of Digital Earth, 2022 Although research on the discrete global grid systems (DGGSs) has become an essential issue in the era of big earth data, there is still a gap between the efficiency of current encoding and operation schemes for hexagonal DGGSs and the needs of practical
Long Zhao +4 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Coordinate Transformation and Polynomial Chaos for the Bayesian Inference of a Gaussian Process with Parametrized Prior Covariance Function [PDF]
, 2015 This paper addresses model dimensionality reduction for Bayesian inference based on prior Gaussian fields with uncertainty in the covariance function hyper-parameters.
I. Sraj, O. Maître, O. Knio, I. Hoteit
semanticscholar +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Designs for thermal harvesting with nonlinear coordinate transformation
AIP Advances, 2018 In this paper a thermal concentrating design method was proposed based on the concept of generating function without knowing the needed coordinate transformation beforehand.
Qingxiang Ji, Guodong Fang, Jun Liang
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Least squares support vector machine model for coordinate transformation
Geodesy and Cartography, 2019 In coordinate transformation, the main purpose is to provide a mathematical relationship between coordinates related to different geodetic reference frames. This gives the geospatial professionals the opportunity to link different datums together. Review
Yao Yevenyo Ziggah +3 more
doaj +1 more source