Results 91 to 100 of about 2,937,580 (310)

An amphoteric and hydrogen-bond-rich artificial α-amino acid for highly durable aqueous redox flow batteries

Nature Communications
Aqueous organic redox flow batteries offer promising prospects for large-scale, high-safety, and cost-effective energy storage systems with no reliance on scarce mineral resources.
Pengbo Zhang, Yuzhu Liu, Jie Wei, Zuoao Wu, Xinmei Song, Guochun Ding, Huaizhu Wang, Junchuan Liang, Zuoxiu Tie, Zhong Jin   +9 more
doaj   +1 more source

The Homocoupling Reaction of Aromatic Terminal Alkynes by a Highly Active Palladium(II)/AgNO3 Cocatalyst in Aqueous Media Under Aerobic Conditions

Molecules, 2016
A new and efficient Pd(II)/AgNO3-cocatalyzed homocoupling of aromatic terminal alkynes is described. Various symmetrical 1,4-disubstituted-1,3-diynes are obtained in good to excellent yields.
Mengping Guo, Bo Chen, Meiyun Lv, Xiuling Zhou, Yongju Wen, Xiuli Shen   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Global research trends in the teacher evaluation of medical college: A bibliometric and visualized study

Heliyon
Background: The evaluation of education in colleges and universities is not only an essential means to promote teachers' professional development and ensure high-quality development of education but also a strong support for the overall development of ...
Yan Song, Yanpeng Jin, Sifan Wang, Jianan Liu, Yanhan Duan, Haoyang Chen, Haijiang Wu   +6 more
doaj   +1 more source

Higher serum uric acid level is inversely associated with renal function assessed by cystatin C in a Japanese general population without chronic kidney disease: the KOBE study

BMC Nephrology, 2019
Background Although several epidemiological studies have suggested that high serum uric acid (SUA) levels are related to a decline in kidney function, only a few studies have investigated using cystatin C to calculate estimated glomerular filtration rate
Sachimi Kubo, Yoko Nishida, Yoshimi Kubota, Aya Higashiyama, Daisuke Sugiyama, Takumi Hirata, Naomi Miyamatsu, Ayumi Tanabe, Aya Hirata, Yukako Tatsumi, Aya Kadota, Kazuyo Kuwabara, Tomofumi Nishikawa, Yoshihiro Miyamoto, Tomonori Okamura   +14 more
doaj   +1 more source

End-to-end thiocyanato-bridged helical chain polymer and dichlorido-bridged copper(II) complexes with a hydrazone ligand: synthesis, characterisation by electron paramagnetic resonance and variable- temperature magnetic studies, and inhibitory effects on human colorectal carcinoma cells [PDF]

, 2012
The reactions of the tridentate hydrazone ligand, N’-[1-(pyridin-2-yl)ethylidene]acetohydrazide (HL), obtained by condensation of 2-acetylpyridine with acetic hyadrazide, with copper nitrate trihydrate in the presence of thiocyanate, or with CuCl2 ...
Das, Kuheli, Datta, Amitabha, Garribba, Eugenio, Hsiao, Ching-Sheng, Hsu, Chin-Lin, Huang, Jui-Hsien, Sinha, Chittaranjan   +6 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

PREDOMOS study, impact of a social intervention program for socially isolated elderly cancer patients: study protocol for a randomized controlled trial

Trials, 2017
Background Cancer incidence and social isolation increase along with advanced age, and social isolation potentiates the relative risk of death by cancer.
Elodie Crétel-Durand, Emilie Nouguerède, Hervé Le Caer, Frédérique Rousseau, Frédérique Retornaz, Olivier Guillem, Anne-Laure Couderc, Laurent Greillier, Emmanuelle Norguet, Maud Cécile, Rabia Boulahssass, Francoise Le Caer, Sandrine Tournier, Chantal Butaud, Pierre Guillet, Sophie Nahon, Laure Poudens, Sylvie Kirscher, Sandrine Loubière, Nadine Diaz, Jean Dhorne, Pascal Auquier, Karine Baumstarck   +22 more
doaj   +1 more source