Results 51 to 60 of about 760,657 (269)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Contexte : Quel modèle de santé animale faut-il promouvoir pour offrir aux éleveurs sahéliens, très mobiles, un accès aux soins vétérinaires facile, continu et de qualité tout en tenant compte de la diversité des contextes locaux ? Pour répondre à cette
Sylvanus Gilles Vias Franck +8 more
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Natural redox-active anthraquinone derivatives possess promising attributes for applications in aqueous organic redox flow batteries (AORFBs) due to their environmental friendliness and abundant sources.
Yuzhu Liu +13 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
This paper provides an overview of coordination constructions in the world's languages.
openaire +3 more sources
On action-angle coordinates and the Poincaré coordinates [PDF]
The first part of this article briefly sketches the work done so far on action-angle coordinates, and then proves their existence along the lines of [\textit{J. J. Duistermaat}, Commun. Pure Appl. Math. 33, 687--706 (1980; Zbl 0439.58014); \textit{V. Guillemin} and \textit{S. Sternberg}, Symplectic techniques in physics.
openaire +3 more sources
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source

