Results 51 to 60 of about 1,547,336 (308)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
SmartMat, 2023 The crystal phases are essential to the physicochemical properties and functionalities of materials. Copper selenide has emerged as an important and appealing semiconductor, which can exist in a variety of polymorphic phases.
Feifan Chen +8 more
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Anticipatory action: Lessons for the future
Frontiers in Climate, 2022 Climate shocks are causing increasingly severe damage and amplifying humanitarian needs. So far, humanitarian action has been mostly responsive, arriving after a crisis has materialized.
Juan Chaves-Gonzalez +9 more
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, 2000 This paper provides an overview of coordination constructions in the world's languages.
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Scandinavian Journal of Primary Health Care, 2022 Objective To investigate how GPs use the PSA test as a diagnostic tool in daily practice.Design Qualitative study using focus group interviews, the transcripts being analyzed by systemic text condensation.Subjects A total of 17 Norwegian GPs in three CME
Olav Thorsen +3 more
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On Reconstruction and Coordination [PDF]
, 1991 This chapter does not have an abstract.
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On games with coordinating and anti-coordinating agents
IFAC-PapersOnLine, 2020 This work studies Nash equilibria for games where a mixture of coordinating and anti-coordinating agents, with possibly heterogeneous thresholds, coexist and interact through an all-to-all network. Whilst games with only coordinating or only anti-coordinating agents are potential, also in the presence of heterogeneities, this does not hold when both ...
Vanelli, Martina +3 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source