Results 61 to 70 of about 1,547,336 (308)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Measuring Strategic Uncertainty in Coordination Games [PDF]

open access: yes
Lecture on the first SFB/TR 15 meeting, Gummersbach, July, 18 - 20, 2004This paper explores predictability of behavior in coordination games with multiple equilibria.
Ockenfels, Peter   +2 more
core   +2 more sources

Tetrachloromethane as an editable all-carbon quaternary source

open access: yesNature Communications
Despite the widespread presence of all-carbon quaternary centers in natural products and bioactive compounds, a concise construction strategy remains very challenging.
Tingrui Li   +6 more
doaj   +1 more source

Vingt ans de services vétérinaires privés de proximité au Niger : enseignements et perspectives pour les politiques publiques

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux
Contexte : Quel modèle de santé animale faut-il promouvoir pour offrir aux éleveurs sahéliens, très mobiles, un accès aux soins vétérinaires facile, continu et de qualité tout en tenant compte de la diversité des contextes locaux ? Pour répondre à cette
Sylvanus Gilles Vias Franck   +8 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Artificial α-amino acid based on cysteine grafted natural aloe-emodin for aqueous organic redox flow batteries

open access: yesNature Communications
Natural redox-active anthraquinone derivatives possess promising attributes for applications in aqueous organic redox flow batteries (AORFBs) due to their environmental friendliness and abundant sources.
Yuzhu Liu   +13 more
doaj   +1 more source

Rhodium-catalysed direct hydroarylation of alkenes and alkynes with phosphines through phosphorous-assisted C−H activation

open access: yesNature Communications, 2019
Dialkyl biaryl phosphines find wide application in catalysis as ligands. Here, the authors report a rhodium-catalysed hydroarylation of alkenes and alkynes with tertiary phosphines through P(III)-chelation assisted C-H activation affording a library of ...
Dingyi Wang   +6 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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