Results 131 to 140 of about 481,621 (347)

Transforming cyclopropanes to enamides via σ-C–C bond eliminative borylation

Nature Communications
Recent strides in C–H borylation have significantly expanded our toolkit for the preparation of organoboronates. Nevertheless, avenues alternative to obtain these compounds via σ-C–C cleavage, thereby facilitating molecular scaffold editing, remain ...
Shuyu Kang, Jiahang Lv, Tianhang Wang, Bingcheng Wu, Minyan Wang, Zhuangzhi Shi   +5 more
doaj   +1 more source

Developing scandium and yttrium coordination chemistry to advance theranostic radiopharmaceuticals [PDF]

, 2020
Korey P. Carter, Gauthier J.‐P. Deblonde, Trevor D. Lohrey, Tyler A. Bailey, Dahlia D. An, Katherine M. Shield, Wayne W. Lukens, Rebecca J. Abergel   +7 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Chiral bidentate phosphabenzene-based ligands: synthesis, coordination chemistry, and application in Rh-catalyzed asymmetric hydrogenations

, 2006
Christian Müller, Leire Guarrotxena López, H. Kooijman, Anthony L. Spek, Dieter Vogt   +4 more
openalex   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Coordination chemistry of microbial iron transport compounds: rhodotorulic acid and iron uptake in Rhodotorula pilimanae [PDF]

, 1978
Carl J. Carrano, Kenneth N. Raymond
openalex   +1 more source

An Autonomous Chemical Robot Discovers the Rules of Inorganic Coordination Chemistry without Prior Knowledge [PDF]

, 2020
Luzian Porwol, Daniel J. Kowalski, Alon Henson, De‐Liang Long, Nicola L. Bell, Leroy Cronin   +5 more
openalex   +1 more source

A focus on coordination chemistry at chlorine. [PDF]

Chem Sci, 2023
Dutton JL.
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source